多形单核细胞抗原的识别。

Recognition of polymorphic monocyte antigens.

作者信息

Jager M J, Paul L C, Persijn G G, van Leeuwen A, van Rood J J

出版信息

Tissue Antigens. 1986 Jan;27(1):15-21. doi: 10.1111/j.1399-0039.1986.tb01493.x.

DOI:10.1111/j.1399-0039.1986.tb01493.x

Abstract

Sera from multiparous women and renal transplant recipients were screened for the presence of anti-monocyte antibodies. Reactions caused by anti-HLA antibodies were excluded by using panel cells that were HLA-compatible with the antibody producers. Six sera with monocyte-specific antibodies were identified, and at least two monocyte-specific (probably allelic) antigens could be recognized. The perspective of the clinical significance of typing for monocyte-specific antigens is discussed.

摘要

对经产妇和肾移植受者的血清进行抗单核细胞抗体检测。通过使用与抗体产生者 HLA 相容的板细胞排除由抗 HLA 抗体引起的反应。鉴定出六种具有单核细胞特异性抗体的血清，并且可以识别至少两种单核细胞特异性（可能是等位基因）抗原。讨论了单核细胞特异性抗原分型的临床意义。