Oelsner G, Graebe R A, Boyers S P, Pan S B, Barnea E R, DeCherney A H
Am J Obstet Gynecol. 1986 Mar;154(3):569-72. doi: 10.1016/0002-9378(86)90603-4.
We compared three methods of ovarian reconstruction in 23 mature female New Zealand White rabbits. Each animal was its own control. The right ovary in each rabbit was incised and repaired by placing three 8-0 nylon sutures through and through the base of the defect (method A). The left ovary was repaired without these through-and-through sutures. In 16, hemostasis was achieved by microbipolar cautery (method B); in seven, hemostasis was achieved with three sutures placed entirely inside the defect (method B1). The cortex of each ovary was repaired identically by continuous 8-0 nylon suture. Outcome was evaluated by laparoscopy 14 days after mating. Through-and-through sutures (right ovary) caused a significant increase in adhesion formation and decrease in nidation index. When these animals were put to death 14 weeks later, the right ovaries were significantly smaller. On the left, there was no difference in any outcome variable between methods B and B1. This study clearly shows the detrimental effect of through-and-through sutures for ovarian reconstruction.
我们在23只成年雌性新西兰白兔身上比较了三种卵巢重建方法。每只动物自身作为对照。每只兔子的右侧卵巢切开后，通过在缺损底部贯穿缝合三根8-0尼龙缝线进行修复（方法A）。左侧卵巢不进行这些贯穿缝合修复。16只兔子通过微型双极电凝止血（方法B）；7只兔子通过在缺损内部完全放置三根缝线止血（方法B1）。每个卵巢的皮质均通过连续8-0尼龙缝线以相同方式修复。在交配14天后通过腹腔镜检查评估结果。贯穿缝合（右侧卵巢）导致粘连形成显著增加，着床指数降低。当这些动物在14周后处死时，右侧卵巢明显更小。在左侧，方法B和方法B1之间的任何结果变量均无差异。这项研究清楚地表明了贯穿缝合对卵巢重建的有害影响。
