Wiskind A K, Toledo A A, Dudley A G, Zusmanis K
Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA 30303.
Am J Obstet Gynecol. 1990 Nov;163(5 Pt 1):1674-8. doi: 10.1016/0002-9378(90)90649-r.
Thirty female New Zealand white rabbits underwent standard laparotomy. Each ovary was bivalved and hemostasis was achieved with bipolar electrocautery. One ovary was then randomized to the closure group, whereas the other ovary was placed in the nonclosure group. In the closure group, the ovarian capsule was closed with a continuous suture of 8-0 Vicryl absorbable surgical suture material with microsurgical technique. In the nonclosure group, the ovaries were left open. Three weeks later the animals were killed and the ovarian adhesions were graded with a standardized scale by an observer (A. A. T.) blinded to the closure status of the animals. Five control animals underwent sham operations with minimal adhesion formation. Statistical analysis of the study animals by the paired Student t test showed a significantly higher adhesion score on the ovaries that were microsurgically closed compared with the ovaries not closed (p = 0.02).
30只雌性新西兰白兔接受了标准剖腹手术。每个卵巢被一分为二，使用双极电灼法止血。然后将一个卵巢随机分配到缝合组，而另一个卵巢则置于未缝合组。在缝合组中，采用显微外科技术，用8-0薇乔可吸收手术缝线材料连续缝合封闭卵巢包膜。在未缝合组中，卵巢保持开放状态。三周后处死动物，由对动物封闭状态不知情的观察者（A.A.T.）使用标准化量表对卵巢粘连情况进行分级。5只对照动物接受了假手术，粘连形成最少。通过配对学生t检验对研究动物进行统计分析，结果显示，与未缝合的卵巢相比，经显微外科缝合的卵巢粘连评分显著更高（p = 0.02）。
