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超重:新型冠状病毒肺炎的一个风险因素——医学难题还是现实?

Overweight: A risk factor for COVID-19 --- A medical conundrum or a reality?

作者信息

Rajiva Rajiva, Faujdar Dharamjeet S, Bobdey Saurabh, Pardal Maninder P S

机构信息

Chief Medical Officer and Consultant (Full Time), THDC India Ltd, Pune, Maharashtra, India.

Department of Community Medicine, Armed Forces Medical College, Pune, Maharashtra, India.

出版信息

J Family Med Prim Care. 2021 Nov;10(11):4096-4101. doi: 10.4103/jfmpc.jfmpc_889_21. Epub 2021 Nov 29.

Abstract

INTRODUCTION

Obesity may contribute to the initiation, progression, transmission, and deterioration of COVID-19. However, there was lack of such studies carried out by Indian workers.

MATERIALS AND METHODS

Data of cumulative cases of COVID-19 of various countries as on the day the peak incidence were reported in each country during the first and second waves of the pandemic was obtained from the internet. Data on prevalence of overweight were obtained by doing a thorough search of existing literature. The data so collected were tabulated and analyzed using SPSS version 20 to establish a correlation coefficient between overweight and COVID-19. Data pertaining to overweight status and age profile and COVID-19 status as on 28 Feb 2021 was collated as part of routine surveillance from the Health Department in an urban area. The total population for which the above data was obtained was 1107. The data so collected were subject to statistical analysis using SPSS version 20, to find out the odds ratio of overweight as a risk factor for COVID-19 after adjusting for age.

RESULTS

Correlation coefficient between overweight and COVID-19 for data pertaining to the first wave and the second wave 0.95 and 0.94, respectively. Odds ratio of overweight as a risk factor for COVID-19 after adjusting for age works out to 2.95 (95% confidence interval 2.30- 3.78). Mean age of the study subjects was 32.61 years (median 32 years, minimum 19 years, maximum 54 years, standard deviation 6.62).

LIMITATIONS

The limitation of the present study is that the workers could only obtain retrospective data, carry out a case-control study and calculate odd ratio for overweight as a risk factor for COVID-19.

摘要

引言

肥胖可能会促使新冠病毒疾病(COVID-19)的发生、发展、传播及病情恶化。然而,印度研究人员尚未开展此类研究。

材料与方法

从互联网获取了在大流行的第一波和第二波期间,各国报告的新冠病毒疾病(COVID-19)累计病例数数据,这些数据是在每个国家报告发病率峰值的当天统计的。通过全面检索现有文献获取超重患病率数据。将收集到的数据制成表格,并使用SPSS 20版进行分析,以确定超重与COVID-19之间的相关系数。作为城市地区卫生部门常规监测的一部分,整理了截至2021年2月28日的超重状况、年龄分布和COVID-19状况的数据。获取上述数据的总人口为1107人。使用SPSS 20版对收集到的数据进行统计分析,以确定在调整年龄因素后,超重作为COVID-19风险因素的比值比。

结果

第一波和第二波数据中,超重与COVID-19的相关系数分别为0.95和0.94。在调整年龄因素后,超重作为COVID-19风险因素的比值比为2.95(95%置信区间2.30 - 3.78)。研究对象的平均年龄为32.61岁(中位数32岁,最小19岁,最大54岁,标准差6.62)。

局限性

本研究的局限性在于研究人员只能获取回顾性数据,开展病例对照研究,并计算超重作为COVID-19风险因素的比值比。

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COVID-19 and Obesity: Dangerous Liaisons.新冠病毒与肥胖症:危险关联
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