Furue M, Ando I, Inoue Y, Tamaki K, Oohara K, Kukita A
Arch Dermatol. 1986 Mar;122(3):310-3. doi: 10.1001/archderm.122.3.310.
A patient with pretibial epidermolysis bullosa was successfully treated with a skin graft. Ultrastructural examination revealed a decreased number of and rudimentary anchoring fibrils (AFs) in the pretibial area in contrast to normal AFs in the grafted skin obtained from a nonpredilection site. Our results indicate the importance of AFs in the pathogenesis of pretibial epidermolysis bullosa.
一名胫前大疱性表皮松解症患者通过皮肤移植成功治愈。超微结构检查显示，与取自非好发部位的移植皮肤中的正常锚原纤维（AFs）相比，胫前区域的AFs数量减少且发育不全。我们的结果表明AFs在胫前大疱性表皮松解症发病机制中的重要性。
