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relA突变在氨基酸饥饿型大肠杆菌存活中的作用。

Role of relA mutation in the survival of amino acid-starved Escherichia coli.

作者信息

Hecker M, Schroeter A, Träder K, Mach F

出版信息

Arch Microbiol. 1986 Jan;143(4):400-2. doi: 10.1007/BF00412809.

DOI:10.1007/BF00412809
PMID:3513732
Abstract

Amino acid-starved cells of Escherichia coli relA+, which contain a large number of glycogen particles, are able to survive in phosphate buffer for a longer time period than their relaxed counterparts. With regard to NH4+ starvation differences in the survival of both strains were not found. NH4+ starved cells of E. coli relA are able to synthesize glycogen but amino acid-starved cells of the relA strain are not. We suggest that the synthesis of glycogen triggered by guanosine tetraphosphate during amino acid starvation is responsible for the prolonged viability of the E. coli relA+ strain.

摘要

含有大量糖原颗粒的大肠杆菌relA +氨基酸饥饿细胞,比其松弛型对应细胞能够在磷酸盐缓冲液中存活更长时间。关于NH4 +饥饿,未发现两种菌株在存活方面存在差异。大肠杆菌relA的NH4 +饥饿细胞能够合成糖原,但relA菌株的氨基酸饥饿细胞则不能。我们认为,氨基酸饥饿期间由四磷酸鸟苷引发的糖原合成是大肠杆菌relA +菌株延长生存能力的原因。

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本文引用的文献

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[Electron microscopic study on plasmas containing desoxyribonucleic acid. I. Nucleoids of actively growing bacteria].[含脱氧核糖核酸血浆的电子显微镜研究。I. 活跃生长细菌的拟核]
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The effect of alcohols on guanosine 5'-diphosphate-3'-diphosphate metabolism in stringent and relaxed Escherichia coli.
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crl mutants of Saccharomyces cerevisiae resemble both mutants affecting general control of amino acid biosynthesis and omnipotent translational suppressor mutants.酿酒酵母的crl突变体既类似于影响氨基酸生物合成一般调控的突变体,也类似于全能翻译抑制突变体。
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Intracellular substrates for endogenous metabolism during long-term starvation of rod and spherical cells of Arthrobacter crystallopoietes.在晶状节杆菌的杆状细胞和球状细胞长期饥饿期间内源性代谢的细胞内底物。
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A modified method for lead staining of thin sections.一种用于薄切片铅染色的改良方法。
J Electron Microsc (Tokyo). 1968;17(2):158-9.
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Stringent control in E. coli.
Annu Rev Genet. 1979;13:393-415. doi: 10.1146/annurev.ge.13.120179.002141.