Departamento de Nutrição - Universidade de Brasília, Brasília, DF - Brasil.
Programa de Pós-graduação em Saúde Coletiva - Universidade de Brasília, Brasília, DF - Brasil.
Arq Bras Cardiol. 2022 Apr;118(4):719-726. doi: 10.36660/abc.20201240.
The prevalence of hypertension and other metabolic disorders has increased in young individuals. However, no representative studies have been conducted in the population of the Federal District, Brazil.
To estimate the prevalence of hypertension and its association with lipid, glucose, and adiposity markers in school-aged adolescents living in the Federal District.
This cross-sectional study included participants of the Study of Cardiovascular Risks in Adolescents (Portuguese acronym, ERICA). Blood pressure, blood glucose, glycated hemoglobin, insulin, homeostatic model assessment for insulin resistance (HOMA-IR), triglycerides, total cholesterol, high-density lipoprotein, low-density lipoprotein, body mass index (BMI), waist circumference, and economic, demographic, and sexual maturity variables were assessed. The data were analyzed in Stata, and the analysis was divided into different stages: descriptive, crude, and adjusted. Significant results were set at p < 0.05.
In total, 1,200 adolescents were included, and their mean age was 14.8 years. The prevalence of hypertension was 8% (95% confidence interval: 6.3; 9.9). Most parameters were associated with blood pressure in crude analysis. In adjusted analysis, glucose, lipid, and adiposity markers maintained the associations, and the highest magnitudes were those of BMI and HOMA-IR.
The study revealed a high prevalence of hypertension in adolescents living in the Federal District, and blood pressure levels were associated with other markers of lipid, glucose, and adiposity profile. The findings indicate the relevance of health surveillance for planning effective actions aimed at reversing this situation and preventing new cases.
高血压和其他代谢紊乱在年轻人中的患病率有所增加。然而,在巴西联邦区的人群中,尚未开展具有代表性的研究。
评估在居住于巴西联邦区的青少年中,高血压的患病率及其与血脂、血糖和肥胖指标的相关性。
本横断面研究纳入了心血管风险青少年研究(葡萄牙语缩写:ERICA)的参与者。评估了血压、血糖、糖化血红蛋白、胰岛素、稳态模型评估的胰岛素抵抗指数(HOMA-IR)、甘油三酯、总胆固醇、高密度脂蛋白、低密度脂蛋白、体重指数(BMI)、腰围以及经济、人口统计学和性成熟变量。使用 Stata 软件分析数据,并将分析分为描述性、未校正和校正三个阶段。具有统计学意义的结果设定为 p < 0.05。
共纳入了 1200 名青少年,平均年龄为 14.8 岁。高血压的患病率为 8%(95%置信区间:6.3%;9.9%)。在粗分析中,大多数参数与血压相关。在校正分析中,血糖、血脂和肥胖标志物与血压仍存在相关性,而 BMI 和 HOMA-IR 的相关性最强。
本研究揭示了居住于巴西联邦区的青少年中高血压的高患病率,且血压水平与其他血脂、血糖和肥胖指标相关。这些发现表明,需要进行健康监测,以制定有效的行动规划,从而扭转这一局面并预防新的病例。