Sharev P N, Vilenskaia M P, Ivanov V G, Shirokova T Iu, Gusorgin V M
Biull Eksp Biol Med. 1986 Mar;101(3):304-6.
The indices of collagen metabolism (free, peptide- and protein bound hydroxyproline) as well as blood plasma proteolytic activity were studied in repeated immobilization (up to 5 days) and skin electropuncture (up to 8 days) in rats. Repeated immobilization (strong stress) steadily increased the contents of free oxyproline and induced undulating changes in the level of other indices under study. Electropuncture (slight stress) produced a short-term increase in free oxyproline blood plasma level. Preliminary and simultaneous electropuncture prevented profound changes in collagen metabolism during immobilization.
在大鼠反复固定（长达5天）和皮肤电针刺激（长达8天）的情况下，研究了胶原蛋白代谢指标（游离、肽结合和蛋白质结合的羟脯氨酸）以及血浆蛋白水解活性。反复固定（强烈应激）使游离羟脯氨酸含量稳步增加，并导致其他所研究指标水平出现波动变化。电针刺激（轻微应激）使血浆游离羟脯氨酸水平出现短期升高。预先进行和同时进行电针刺激可防止固定过程中胶原蛋白代谢发生深刻变化。
