Dermatology Department, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Department of Medicine, University of Melbourne, Parkville, Victoria, Australia.
Australas J Dermatol. 2022 May;63(2):e155-e158. doi: 10.1111/ajd.13803. Epub 2022 Feb 9.
Since the concurrence of bullous pemphigoid (BP) and psoriasis was first reported in 1929, an increasing number of studies has been published to analyse their relationship in recent years. However, the pathogenesis of the concurrence is not yet well understood, and the coexistence of the two conditions imposes a difficult therapeutic challenge. This case report demonstrates the first case of secukinumab achieving a dramatic clinical improvement of both chronic psoriasis and active BP.
自 1929 年首次报道大疱性类天疱疮（BP）与银屑病并发以来，近年来越来越多的研究分析了它们之间的关系。然而，其并发的发病机制尚未完全阐明，两种疾病的共存给治疗带来了很大的挑战。本病例报告首次展示了司库奇尤单抗可显著改善慢性银屑病和活动性 BP 的临床症状。
