• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The cholinergic hypothesis--ten years on.

作者信息

Perry E K

出版信息

Br Med Bull. 1986 Jan;42(1):63-9. doi: 10.1093/oxfordjournals.bmb.a072100.

DOI:10.1093/oxfordjournals.bmb.a072100
PMID:3513895
Abstract
摘要

相似文献

1
The cholinergic hypothesis--ten years on.胆碱能假说——十年之后
Br Med Bull. 1986 Jan;42(1):63-9. doi: 10.1093/oxfordjournals.bmb.a072100.
2
Mild cognitive impairment and the cholinergic hypothesis: a very different take on recent data.轻度认知障碍与胆碱能假说：对近期数据的一种截然不同的解读。
Ann Neurol. 2002 Sep;52(3):384-5. doi: 10.1002/ana.10308.
3
Choline metabolism in cholinergic neurons: implications for the pathogenesis of neurodegenerative diseases.
Adv Neurol. 1990;51:117-25.
4
Advances in the biology of cholinergic neurons.
Adv Neurol. 1990;51:109-15.
5
Microsphere embolism-induced cortical cholinergic deafferentation and impairments in attentional performance.微球栓塞诱导的皮质胆碱能传入缺失及注意力表现受损。
Eur J Neurosci. 2005 Jun;21(11):3117-32. doi: 10.1111/j.1460-9568.2005.04136.x.
6
The significance of the cholinergic system in the brain during aging and in Alzheimer's disease.衰老及阿尔茨海默病期间大脑中胆碱能系统的意义。
J Neural Transm (Vienna). 2006 Nov;113(11):1625-44. doi: 10.1007/s00702-006-0579-2. Epub 2006 Oct 13.
7
Revisiting the cholinergic hypothesis of behavioral and psychological symptoms in dementia of the Alzheimer's type.重新审视阿尔茨海默病痴呆行为和心理症状的胆碱能假说。
Ageing Res Rev. 2011 Sep;10(4):404-12. doi: 10.1016/j.arr.2011.01.003. Epub 2011 Feb 1.
8
[Current concepts on the hypothesis of the cholinergic etiology of Alzheimer's disease ].
Recenti Prog Med. 1986 Sep;77(9):436-9.
9
Cholinergic markers in the early diagnosis of Alzheimer's disease.
Bull Clin Neurosci. 1985;50:49-52.
10
Loss of cholinergic pathways in vascular dementia of the Binswanger type.宾斯万格型血管性痴呆中胆碱能通路的丧失。
Dement Geriatr Cogn Disord. 2005;19(5-6):282-8. doi: 10.1159/000084553. Epub 2005 Mar 21.

引用本文的文献

1
Identification of specialized metabolites from Artocarpus lacucha as potent α-glucosidase and acetylcholinesterase inhibitors: enzyme kinetic, in vitro and in silico study.从白桂木中鉴定出作为强效α-葡萄糖苷酶和乙酰胆碱酯酶抑制剂的特殊代谢产物：酶动力学、体外和计算机模拟研究
J Nat Med. 2025 May 6. doi: 10.1007/s11418-025-01904-8.
2
Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.阿加曲班与丁苯酞序贯治疗对急性脑梗死患者神经功能及血液流变学的影响
Medicine (Baltimore). 2024 Jun 14;103(24):e38067. doi: 10.1097/MD.0000000000038067.
3
Metal-Organic Frameworks as Sensors for Human Amyloid Diseases.
金属有机框架作为人类淀粉样疾病的传感器。
ACS Sens. 2023 Mar 24;8(3):1033-1053. doi: 10.1021/acssensors.2c02741. Epub 2023 Mar 9.
4
Alternative Pharmacological Strategies for the Treatment of Alzheimer's Disease: Focus on Neuromodulator Function.治疗阿尔茨海默病的替代药理学策略：聚焦神经调节剂功能
Biomedicines. 2022 Nov 28;10(12):3064. doi: 10.3390/biomedicines10123064.
5
Anti-cholinergic drug burden in patients with dementia increases after hospital admission: a multicentre cross-sectional study.痴呆患者住院后抗胆碱能药物负担增加：一项多中心横断面研究。
BMC Geriatr. 2022 Oct 6;22(1):783. doi: 10.1186/s12877-022-03235-9.
6
Antiacetylcholinesterase triterpenes from the fruits of .来自……果实的抗乙酰胆碱酯酶三萜类化合物 。 你提供的原文不完整，句末缺少具体信息。
RSC Adv. 2018 Feb 19;8(14):7832-7838. doi: 10.1039/c8ra00291f. eCollection 2018 Feb 14.
7
Drug Design Targeting the Muscarinic Receptors and the Implications in Central Nervous System Disorders.靶向毒蕈碱受体的药物设计及其对中枢神经系统疾病的影响
Biomedicines. 2022 Feb 7;10(2):398. doi: 10.3390/biomedicines10020398.
8
Non-Alkaloid Cholinesterase Inhibitory Compounds from Natural Sources.天然来源的非碱性胆碱酯酶抑制剂化合物。
Molecules. 2021 Sep 14;26(18):5582. doi: 10.3390/molecules26185582.
9
Precision and False Perceptual Inference.精确性与错误的感知推理
Front Integr Neurosci. 2018 Sep 20;12:39. doi: 10.3389/fnint.2018.00039. eCollection 2018.
10
Comparison of Memory Impairment and Oxidative Stress Following Single or Repeated Doses Administration of Scopolamine in Rat Hippocampus.东莨菪碱单次或重复给药大鼠海马后记忆损伤与氧化应激的比较
Basic Clin Neurosci. 2018 Jan-Feb;9(1):5-14. doi: 10.29252/NIRP.BCN.9.1.5.