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COVID-19 大流行对生命科学领域科研的影响。

The impact of the COVID-19 pandemic on scientific research in the life sciences.

机构信息

AXES, IMT School for Advanced Studies Lucca, Lucca, Italy.

Chair of Systems Design D-MTEC, ETH Zürich, Zurich, Switzerland.

出版信息

PLoS One. 2022 Feb 9;17(2):e0263001. doi: 10.1371/journal.pone.0263001. eCollection 2022.

Abstract

The COVID-19 outbreak has posed an unprecedented challenge to humanity and science. On the one side, public and private incentives have been put in place to promptly allocate resources toward research areas strictly related to the COVID-19 emergency. However, research in many fields not directly related to the pandemic has been displaced. In this paper, we assess the impact of COVID-19 on world scientific production in the life sciences and find indications that the usage of medical subject headings (MeSH) has changed following the outbreak. We estimate through a difference-in-differences approach the impact of the start of the COVID-19 pandemic on scientific production using the PubMed database (3.6 Million research papers). We find that COVID-19-related MeSH terms have experienced a 6.5 fold increase in output on average, while publications on unrelated MeSH terms dropped by 10 to 12%. The publication weighted impact has an even more pronounced negative effect (-16% to -19%). Moreover, COVID-19 has displaced clinical trial publications (-24%) and diverted grants from research areas not closely related to COVID-19. Note that since COVID-19 publications may have been fast-tracked, the sudden surge in COVID-19 publications might be driven by editorial policy.

摘要

新冠疫情的爆发对人类和科学界构成了前所未有的挑战。一方面,公共和私人激励措施已经到位,以便将资源迅速分配到与新冠疫情紧急情况严格相关的研究领域。然而,许多与大流行不直接相关的领域的研究已经被取代。本文评估了新冠疫情对生命科学领域世界科学产出的影响,并发现有迹象表明,在疫情爆发后,医学主题词(MeSH)的使用发生了变化。我们使用 PubMed 数据库(360 万篇研究论文)通过差异中的差异方法估计新冠疫情开始对科学产出的影响。我们发现,与新冠相关的 MeSH 术语的产出平均增长了 6.5 倍,而与不相关的 MeSH 术语相关的出版物下降了 10%至 12%。按出版物加权的影响甚至有更明显的负面影响(-16%至-19%)。此外,新冠疫情已经取代了临床试验出版物(-24%),并从与新冠疫情没有密切关系的研究领域转移了资金。请注意,由于新冠疫情相关的出版物可能已经得到了快速处理,因此新冠疫情相关出版物的突然激增可能是由编辑政策推动的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ab7/8827464/e3a80986bac8/pone.0263001.g001.jpg

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