2003年至2023年沙特阿拉伯的登革病毒感染：系统评价与荟萃分析
Dengue virus infection in Saudi Arabia from 2003 to 2023: a systematic review and meta-analysis.
作者信息
Rabaan Ali A, Alshengeti Amer, Alrasheed Hayam A, Al-Subaie Maha F, Aljohani Maha H, Almutawif Yahya A, Yousuf Amjad A, Alsuliman Shahab A, Al-Jishi Jumana M, Almalki Fareed, Alshiekheid Maha A, Alahmed Hejji E, Alramadan Ameen M, Turkistani Safaa Abdulrahman, Hajissa Khalid
机构信息
College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
出版信息
Pathog Glob Health. 2024 Oct-Dec;118(7-8):549-558. doi: 10.1080/20477724.2024.2425493. Epub 2024 Nov 7.
Dengue virus (DENV) remains one of the most common arboviral infections threatening humans. This study was conducted to systematically review the available literature and provide an updated overview of the overall prevalence of DENV infection in Saudi Arabia. The prevalence data was pooled from 21,891 participants recruited in 17 studies. Using random-effects model, the overall prevalence of DENV infection in Saudi Arabia was calculated as 30.8% (95% CI: 20.8-49.8%). The pooled IgM and IgG seroprevalence rates were 17.7% and 26.6%, respectively. Furthermore, the detection of DENV-NS1 antigen and viral RNA revealed pooled estimates of 16.4% and 37.0%, respectively. This study reports a relatively high burden of DENV infection in Saudi Arabia. The findings of this SRMA provide valuable information on the epidemiology of DENV infections in the country, highlighting the need for additional epidemiological investigations to assess the current situation of DENV infection in the country.
登革病毒（DENV）仍然是威胁人类的最常见虫媒病毒感染之一。本研究旨在系统回顾现有文献，并提供沙特阿拉伯登革病毒感染总体流行情况的最新概述。患病率数据来自17项研究中招募的21891名参与者。采用随机效应模型，计算出沙特阿拉伯登革病毒感染的总体患病率为30.8%（95%置信区间：20.8-49.8%）。IgM和IgG血清阳性率的合并率分别为17.7%和26.6%。此外，DENV-NS1抗原和病毒RNA的检测显示合并估计值分别为16.4%和37.0%。本研究报告了沙特阿拉伯登革病毒感染负担相对较高。本系统综述和荟萃分析（SRMA）的结果提供了该国登革病毒感染流行病学的宝贵信息，强调需要进行更多的流行病学调查以评估该国登革病毒感染的现状。
Zotero 插件