Centre for Epidemiological Research, Nykøbing Falster Hospital, Nykøbing Falster, Denmark.
Omicron ApS, Roskilde, Denmark.
Scand J Public Health. 2023 Aug;51(6):853-861. doi: 10.1177/14034948221075023. Epub 2022 Feb 9.
In Denmark, rural-provincial Lolland-Falster currently has the highest mortality, caused mainly by the high mortality of in-migrating people. To identify possible preventive measures to combat this excess mortality insight into the underlying diseases is needed.
We used data from Danish registers to calculate cause-specific mortality for 1970-1979, 1980-1989, 1990-1999, 2000-2009 and 2010-2018 divided into cancer, cardiovascular diseases, respiratory diseases, external causes and other causes (all remaining causes). We calculated age-standardised mortality rates for Lolland-Falster and the rest of Denmark: mortality rate ratios and excess number of deaths per 100,000 person-years for Lolland-Falster distinguishing between long-term residents (10+ years) and in-migrants.
In 1970-1979, the age-standardised mortality rates for Lolland-Falster resembled those for rest of Denmark. Over time, age-standardised mortality rates for cardiovascular diseases decreased but more so for the rest of Denmark than for Lolland-Falster. Age-standardised mortality rates for other diseases increased but more so for Lolland-Falster than for the rest of Denmark. The excess mortality in Lolland-Falster derived in particular from in-migrants: in 2010-2018 the mortality rate ratios for this population reached 2.29 (95% confidence interval 1.96-2.69) for external causes and 2.12 (95% confidence interval 1.97-2.29) for other diseases. In-migrants had in total 411 excess deaths per 100,000 person-years. Of these 27% came from tobacco smoking-related causes of death. However, another 25% came from ill-defined, unspecified and a broad range of other, minor causes of deaths.
在丹麦，农村省份洛兰-法尔斯特（Lolland-Falster）目前的死亡率最高，主要是由于移民的高死亡率所致。为了确定可能的预防措施来应对这种超额死亡，需要深入了解潜在的疾病。
我们使用丹麦登记处的数据，计算了 1970-1979 年、1980-1989 年、1990-1999 年、2000-2009 年和 2010-2018 年的特定原因死亡率，分为癌症、心血管疾病、呼吸系统疾病、外部原因和其他原因（所有剩余原因）。我们为洛兰-法尔斯特和丹麦其他地区计算了年龄标准化死亡率：死亡率比和每 10 万人年的超额死亡人数，区分长期居民（10 年以上）和移民。
在 1970-1979 年，洛兰-法尔斯特的年龄标准化死亡率与丹麦其他地区相似。随着时间的推移，心血管疾病的年龄标准化死亡率下降，但在丹麦其他地区下降幅度大于洛兰-法尔斯特。其他疾病的年龄标准化死亡率上升，但在洛兰-法尔斯特上升幅度大于丹麦其他地区。洛兰-法尔斯特的超额死亡主要来自移民：在 2010-2018 年，这一人群的死亡率比达到 2.29（95%置信区间 1.96-2.69），外部原因和其他疾病分别为 2.12（95%置信区间 1.97-2.29）。移民每 10 万人年有 411 例超额死亡。其中 27%来自与吸烟有关的死亡原因。然而，另外 25%来自未明确、未具体和广泛的其他较小的死亡原因。
