Department of Otolaryngology, Head and Neck Surgery Unit, Alexandria Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Clinical Pathology, Alexandria Faculty of Medicine, Alexandria University, Alexandria, Egypt.
J Laryngol Otol. 2022 Aug;136(8):737-741. doi: 10.1017/S0022215121004564. Epub 2022 Feb 10.
Platelet-rich plasma has gained interest over the two last decades, mainly because of its role in regenerative medicine. This work aimed to assess the role of intra-operative local application of platelet-rich plasma gel in the improvement of quality of voice after microlaryngeal surgery.
This was a prospective comparative study that included 40 patients undergoing microlaryngeal surgery for benign vocal fold lesions. There were two groups divided equally into study group A and control group B. The assessment of voice was performed by videostroboscopy and acoustic analysis pre-operatively and at two weeks and one and three months post-operatively.
The data demonstrated that all the stroboscopic and acoustic parameters showed significant improvement in both groups. Group A showed significant improvement regarding acoustic parameters at the third post-operative follow up when compared with group B.
Platelet-rich plasma has a beneficial effect on voice quality following microlaryngeal surgery based in particular on acoustic parameters.
富血小板血浆在过去二十年中引起了人们的兴趣，主要是因为它在再生医学中的作用。本研究旨在评估术中局部应用富血小板血浆凝胶在改善微创声带手术后嗓音质量中的作用。
这是一项前瞻性的对照研究，共纳入 40 例因良性声带病变而行微创声带手术的患者。将患者分为两组，即研究组 A 和对照组 B，每组各 20 例。通过频闪喉镜和声学分析，在术前、术后 2 周、1 个月和 3 个月对嗓音进行评估。
数据显示，两组患者的所有频闪喉镜和声学参数均有显著改善。与对照组 B 相比，研究组 A 在术后 3 个月的随访时在声学参数方面显示出显著改善。
富血小板血浆对微创声带手术后的嗓音质量有有益的影响，特别是在声学参数方面。
