Travers A A, Buckland R, Goman M, Le Grice S S, Scaife J G
Nature. 1978 Jun 1;273(5661):354-8. doi: 10.1038/273354a0.
The RNA polymerase mutation, alt-1, affects the sigma subunit and alters the in vitro selectivity of RNA polymerase to parallel the in vivo phenotype. We propose that the mutation changes the distribution of functionally distinct polymerase isomers.
RNA聚合酶突变体alt-1影响σ亚基,并改变RNA聚合酶的体外选择性,使其与体内表型一致。我们认为,该突变改变了功能不同的聚合酶异构体的分布。