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基于前庭脊髓反射补充检查的中枢性前庭疾病诊断

The diagnosis of central vestibular disorders based on the complementary examination of the vestibulospinal reflex.

作者信息

Maihoub Stefani, Molnár András, Tamás László, Szirmai Ágnes

机构信息

Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

出版信息

J Otol. 2022 Jan;17(1):1-4. doi: 10.1016/j.joto.2021.07.001. Epub 2021 Jul 3.

Abstract

OBJECTIVES

Stance and gait unsteadiness along with vertigo contribute to a central vestibular disorder. For objective analysis ultrasound-computer-craniocorpography (US-COMP-CCG) can be used. Aim of the study was to characterize the unsteadiness in central vestibular disorders and discuss the possible diagnostic usage of US-COMP-CCG.

METHODS AND RESULTS

Hundred-and-ninety patients (70 male and 120 female, mean age ± SD, 58.94 ± 15.27) suffering from central vestibular disorder and 230 healthy control patients (78 male and 152 female, mean age ± SD, 50.94 ± 15.27) were enrolled. Stance and gait analysis was according to vestibulospinal tests of US-COMPCCG. IBM SPSS V24 software was used for statistical analysis. Mann-Whitney test and Chi-square test were used, along with sensitivity and specificity categorization. The significance level was p < 0.05. According to schematic and statistical analysis instability and postural sway were increased in the vertigo population and statistically significant difference was shown. Upon categorical analysis significant correlation was detected [standing test: longitudinal sway (p < 0.00001), lateral sway (p < 0.00001), forehead covering area parameters (p = 0.0001); stepping test: longitudinal deviation (p = 0.05), lateral sway (p = 0.011) parameters].

CONCLUSIONS

Clinicians should consider that postural instability is prominently present in this population and might be of a diagnostic importance.

摘要

目的

姿势和步态不稳以及眩晕是中枢性前庭疾病的表现。可使用超声计算机颅体描记术(US-COMP-CCG)进行客观分析。本研究的目的是描述中枢性前庭疾病中的不稳情况,并探讨US-COMP-CCG可能的诊断用途。

方法与结果

纳入190例中枢性前庭疾病患者(男性70例,女性120例,平均年龄±标准差,58.94±15.27)和230例健康对照者(男性78例,女性152例,平均年龄±标准差,50.94±15.27)。姿势和步态分析依据US-COMP-CCG的前庭脊髓测试。使用IBM SPSS V24软件进行统计分析。采用曼-惠特尼检验和卡方检验,以及敏感性和特异性分类。显著性水平为p < 0.05。根据图表和统计分析,眩晕人群的不稳定性和姿势摆动增加,差异具有统计学意义。分类分析显示存在显著相关性[站立测试:纵向摆动(p < 0.00001)、横向摆动(p < 0.00001)、前额覆盖面积参数(p = 0.0001);步测:纵向偏差(p = 0.05)、横向摆动(p = 0.011)参数]。

结论

临床医生应认识到该人群中姿势不稳较为突出,可能具有诊断意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c23/8811398/f1769313d67a/gr1.jpg

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