Maihoub Stefani, Molnár András, Tamás László, Szirmai Ágnes
Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
J Otol. 2022 Jan;17(1):1-4. doi: 10.1016/j.joto.2021.07.001. Epub 2021 Jul 3.
Stance and gait unsteadiness along with vertigo contribute to a central vestibular disorder. For objective analysis ultrasound-computer-craniocorpography (US-COMP-CCG) can be used. Aim of the study was to characterize the unsteadiness in central vestibular disorders and discuss the possible diagnostic usage of US-COMP-CCG.
Hundred-and-ninety patients (70 male and 120 female, mean age ± SD, 58.94 ± 15.27) suffering from central vestibular disorder and 230 healthy control patients (78 male and 152 female, mean age ± SD, 50.94 ± 15.27) were enrolled. Stance and gait analysis was according to vestibulospinal tests of US-COMPCCG. IBM SPSS V24 software was used for statistical analysis. Mann-Whitney test and Chi-square test were used, along with sensitivity and specificity categorization. The significance level was p < 0.05. According to schematic and statistical analysis instability and postural sway were increased in the vertigo population and statistically significant difference was shown. Upon categorical analysis significant correlation was detected [standing test: longitudinal sway (p < 0.00001), lateral sway (p < 0.00001), forehead covering area parameters (p = 0.0001); stepping test: longitudinal deviation (p = 0.05), lateral sway (p = 0.011) parameters].
Clinicians should consider that postural instability is prominently present in this population and might be of a diagnostic importance.
姿势和步态不稳以及眩晕是中枢性前庭疾病的表现。可使用超声计算机颅体描记术(US-COMP-CCG)进行客观分析。本研究的目的是描述中枢性前庭疾病中的不稳情况,并探讨US-COMP-CCG可能的诊断用途。
纳入190例中枢性前庭疾病患者(男性70例,女性120例,平均年龄±标准差,58.94±15.27)和230例健康对照者(男性78例,女性152例,平均年龄±标准差,50.94±15.27)。姿势和步态分析依据US-COMP-CCG的前庭脊髓测试。使用IBM SPSS V24软件进行统计分析。采用曼-惠特尼检验和卡方检验,以及敏感性和特异性分类。显著性水平为p < 0.05。根据图表和统计分析,眩晕人群的不稳定性和姿势摆动增加,差异具有统计学意义。分类分析显示存在显著相关性[站立测试:纵向摆动(p < 0.00001)、横向摆动(p < 0.00001)、前额覆盖面积参数(p = 0.0001);步测:纵向偏差(p = 0.05)、横向摆动(p = 0.011)参数]。
临床医生应认识到该人群中姿势不稳较为突出,可能具有诊断意义。