药物治疗依从性不佳作为阿哌沙班治疗静脉血栓栓塞失败的原因：药师药物重整的重要性。
Medication non-adherence as a cause of apixaban failure in venous thromboembolism: The importance of pharmacist medication reconciliation.
作者信息
Jethwa Trisha E, Moran Kaitlin M, Maniaci Michael J
机构信息
Department of Family Medicine Mayo Clinic in Florida Jacksonville Florida USA.
Department of Internal Medicine Mayo Clinic in Florida Jacksonville Florida USA.
出版信息
Clin Case Rep. 2022 Feb 2;10(2):e05338. doi: 10.1002/ccr3.5338. eCollection 2022 Feb.
Abstract
Venous thromboembolism is often treated with direct oral anticoagulants. In order for direct oral anticoagulants to be effective, patients must adhere to a specific dosing strategy. We report a case of apixaban failure, the clinical workup that ensued, and the eventual discovery of unsuccessful medication adherence as the cause.
摘要
静脉血栓栓塞症通常采用直接口服抗凝剂进行治疗。为使直接口服抗凝剂发挥疗效，患者必须遵循特定的给药策略。我们报告一例阿哌沙班治疗失败的病例，后续的临床检查情况，以及最终发现用药依从性不佳是导致治疗失败的原因。
相似文献
1
Medication non-adherence as a cause of apixaban failure in venous thromboembolism: The importance of pharmacist medication reconciliation.药物治疗依从性不佳作为阿哌沙班治疗静脉血栓栓塞失败的原因：药师药物重整的重要性。
Clin Case Rep. 2022 Feb 2;10(2):e05338. doi: 10.1002/ccr3.5338. eCollection 2022 Feb.
2
Efficacy and safety of direct oral factor Xa inhibitors compared with warfarin in patients with morbid obesity: a single-centre, retrospective analysis of chart data.与华法林相比，直接口服Xa因子抑制剂在病态肥胖患者中的疗效和安全性：一项单中心图表数据回顾性分析
Lancet Haematol. 2019 Jul;6(7):e359-e365. doi: 10.1016/S2352-3026(19)30086-9. Epub 2019 May 24.
3
Safety and Efficacy of Apixaban vs Enoxaparin for Preventing Postoperative Venous Thromboembolism in Women Undergoing Surgery for Gynecologic Malignant Neoplasm: A Randomized Clinical Trial.阿哌沙班与依诺肝素预防妇科恶性肿瘤女性手术患者术后静脉血栓栓塞症的安全性和有效性：一项随机临床试验。
JAMA Netw Open. 2020 Jun 1;3(6):e207410. doi: 10.1001/jamanetworkopen.2020.7410.
4
Effectiveness and safety of apixaban versus rivaroxaban for prevention of recurrent venous thromboembolism and adverse bleeding events in patients with venous thromboembolism: a retrospective population-based cohort analysis.阿哌沙班与利伐沙班预防静脉血栓栓塞症患者复发性静脉血栓栓塞和不良出血事件的有效性及安全性：一项基于人群的回顾性队列分析。
Lancet Haematol. 2019 Jan;6(1):e20-e28. doi: 10.1016/S2352-3026(18)30191-1. Epub 2018 Dec 14.
5
Comparison of medication adherence to different oral anticoagulants: population-based cohort study.不同口服抗凝药物的用药依从性比较：基于人群的队列研究。
BMJ Open. 2023 Jan 5;13(1):e065700. doi: 10.1136/bmjopen-2022-065700.
6
Patient satisfaction after conversion from warfarin to direct oral anticoagulants for patients on extended duration of anticoagulation for venous thromboembolism - The SWAN Study.静脉血栓栓塞症抗凝延长治疗患者换用直接口服抗凝剂后对患者满意度的影响：SWAN 研究。
PLoS One. 2020 Jun 4;15(6):e0234048. doi: 10.1371/journal.pone.0234048. eCollection 2020.
7
Drug Utilization Pattern of Oral Anticoagulants in Patients with Atrial Fibrillation: A Nationwide Population-Based Study in Korea.口服抗凝药物在心房颤动患者中的用药模式：韩国全国范围内基于人群的研究。
Adv Ther. 2022 Jul;39(7):3112-3130. doi: 10.1007/s12325-022-02151-z. Epub 2022 May 7.
8
Adherence to apixaban for extended thromboprophylaxis after major abdominal or pelvic surgery for cancer: A prospective cohort study.癌症患者腹部或骨盆大手术后延长使用阿哌沙班进行血栓预防的依从性：一项前瞻性队列研究。
J Surg Oncol. 2022 Aug;126(2):386-393. doi: 10.1002/jso.26876. Epub 2022 Apr 1.
9
Patient education program for venous thromboembolism prevention in hospitalized patients.患者教育计划预防住院患者静脉血栓栓塞症。
Am J Med. 2012 Mar;125(3):258-64. doi: 10.1016/j.amjmed.2011.09.012.
10
Apixaban versus no anticoagulation for the prevention of venous thromboembolism in children with newly diagnosed acute lymphoblastic leukaemia or lymphoma (PREVAPIX-ALL): a phase 3, open-label, randomised, controlled trial.依度沙班与不抗凝治疗用于预防新发急性淋巴细胞白血病或淋巴瘤儿童的静脉血栓栓塞症（PREVAPIX-ALL）：一项 3 期、开放标签、随机、对照试验。
Lancet Haematol. 2024 Jan;11(1):e27-e37. doi: 10.1016/S2352-3026(23)00314-9. Epub 2023 Nov 16.
引用本文的文献
1
Trust but verify: A case report of unintended medication omission.宁可信其无：一例意外漏服药物的病例报告。
Clin Case Rep. 2023 Jan 3;11(1):e6800. doi: 10.1002/ccr3.6800. eCollection 2023 Jan.
本文引用的文献
1
Assessing the impact of virtual medication history technicians on medication reconciliation discrepancies.评估虚拟用药史技术员对用药重整差异的影响。
Int J Clin Pharm. 2021 Oct;43(5):1404-1411. doi: 10.1007/s11096-021-01267-6. Epub 2021 Apr 19.
2
Treatment Failures of Direct Oral Anticoagulants.直接口服抗凝剂治疗失败。
Am J Ther. 2021;28(1):e87-e95. doi: 10.1097/MJT.0000000000001083.
3
Systematic review and meta-analysis of the efficacy and safety of apixaban compared to rivaroxaban in acute VTE in the real world.系统评价和荟萃分析阿哌沙班与利伐沙班在真实世界中治疗急性 VTE 的疗效和安全性。
Blood Adv. 2019 Aug 13;3(15):2381-2387. doi: 10.1182/bloodadvances.2019000572.
4
The Teach Back Project: A System-wide Evidence Based Practice Implementation.反馈教学项目：全系统基于证据的实践实施
J Pediatr Nurs. 2018 Sep-Oct;42:81-85. doi: 10.1016/j.pedn.2018.06.002. Epub 2018 Jul 21.
5
Efficacy and safety of direct oral anticoagulants approved for cardiovascular indications: Systematic review and meta-analysis.已批准用于心血管适应证的直接口服抗凝剂的疗效和安全性：系统评价和荟萃分析。
PLoS One. 2018 May 24;13(5):e0197583. doi: 10.1371/journal.pone.0197583. eCollection 2018.
6
Guidance for the practical management of the direct oral anticoagulants (DOACs) in VTE treatment.直接口服抗凝剂（DOACs）在VTE治疗中的实际管理指南。
J Thromb Thrombolysis. 2016 Jan;41(1):206-32. doi: 10.1007/s11239-015-1310-7.
7
The epidemiology of venous thromboembolism.静脉血栓栓塞症的流行病学
J Thromb Thrombolysis. 2016 Jan;41(1):3-14. doi: 10.1007/s11239-015-1311-6.
8
The impact of teach-back on comprehension of discharge instructions and satisfaction among emergency patients with limited health literacy: A randomized, controlled study.回授法对健康素养有限的急诊患者出院指导理解及满意度的影响：一项随机对照研究
J Commun Healthc. 2015 Mar;8(1):10-21. doi: 10.1179/1753807615Y.0000000001.
9
Transitions of care in anticoagulated patients.抗凝治疗患者的治疗过渡期。
J Multidiscip Healthc. 2013 Jun 20;6:215-28. doi: 10.2147/JMDH.S44068. Print 2013.
10
Using "teach-back" to promote a safe transition from hospital to home: an evidence-based approach to improving the discharge process.使用“回授”促进从医院到家庭的安全过渡：一种基于证据的改善出院流程的方法。
J Pediatr Nurs. 2013 May-Jun;28(3):282-91. doi: 10.1016/j.pedn.2012.10.007. Epub 2012 Dec 5.
Zotero 插件