• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

抗血管内皮生长因子（VEGF）疗法治疗中枢神经系统急性髓系白血病复发的疗效：一例病例报告及文献综述

Efficiency of anti-VEGF therapy in central nervous system AML relapse: A case report and literature review.

作者信息

Cao Han-Yu, Tao Tao, Shen Xiang-Dong, Bai Lian, Wan Chao-Ling, Wu De-Pei, Li Jin-Li, Xue Sheng-Li

机构信息

National Clinical Research Center for Hematologic Diseases Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou China.

Institute of Blood and Marrow Transplantation Collaborative Innovation Center of Hematology Soochow University Suzhou China.

出版信息

Clin Case Rep. 2022 Feb 3;10(2):e05367. doi: 10.1002/ccr3.5367. eCollection 2022 Feb.

DOI:10.1002/ccr3.5367
PMID:35140963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8813665/
Abstract

There have been few reports on the treatment of central nervous system (CNS) acute myeloid leukemia (AML) relapse. This case study demonstrates that bevacizumab may be a viable treatment option when combined with IT chemotherapy as maintenance therapy for those with CNS leukemia.

摘要

关于中枢神经系统（CNS）急性髓系白血病（AML）复发的治疗报告较少。本病例研究表明，对于中枢神经系统白血病患者，贝伐单抗与鞘内化疗联合作为维持治疗可能是一种可行的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/015b/8813665/60534d11eaa8/CCR3-10-e05367-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/015b/8813665/f49a1a83de23/CCR3-10-e05367-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/015b/8813665/d86bf1a708be/CCR3-10-e05367-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/015b/8813665/60534d11eaa8/CCR3-10-e05367-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/015b/8813665/f49a1a83de23/CCR3-10-e05367-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/015b/8813665/d86bf1a708be/CCR3-10-e05367-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/015b/8813665/60534d11eaa8/CCR3-10-e05367-g004.jpg

相似文献

1
Efficiency of anti-VEGF therapy in central nervous system AML relapse: A case report and literature review.抗血管内皮生长因子（VEGF）疗法治疗中枢神经系统急性髓系白血病复发的疗效：一例病例报告及文献综述
Clin Case Rep. 2022 Feb 3;10(2):e05367. doi: 10.1002/ccr3.5367. eCollection 2022 Feb.
2
Impact of prophylactic intrathecal chemotherapy on CNS relapse rates in AML patients presenting with hyperleukocytosis.预防性鞘内化疗对伴有白细胞增多的 AML 患者中枢神经系统复发率的影响。
Leuk Lymphoma. 2020 Apr;61(4):862-868. doi: 10.1080/10428194.2019.1691199. Epub 2019 Nov 18.
3
Effects of Total Body Irradiation on Hematopoietic Cell Transplantation Outcomes in Pediatric Acute Myeloid Leukemia with Prior Central Nervous System Involvement.全身照射对伴有中枢神经系统累及的儿童急性髓系白血病造血细胞移植结局的影响。
Transplant Cell Ther. 2024 Aug;30(8):812.e1-812.e11. doi: 10.1016/j.jtct.2024.05.014. Epub 2024 May 18.
4
Central nervous system involvement in acute lymphoblastic leukemia is mediated by vascular endothelial growth factor.中枢神经系统在急性淋巴细胞白血病中的参与是由血管内皮生长因子介导的。
Blood. 2017 Aug 3;130(5):643-654. doi: 10.1182/blood-2017-03-769315. Epub 2017 May 26.
5
Outcome of allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia patients with central nervous system involvement.急性髓系白血病合并中枢神经系统受累患者异基因造血干细胞移植的结局
Biol Blood Marrow Transplant. 2014 Dec;20(12):2029-33. doi: 10.1016/j.bbmt.2014.09.001. Epub 2014 Sep 6.
6
Prognosis and risk factors for central nervous system relapse after allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia.异基因造血干细胞移植后急性髓系白血病中枢神经系统复发的预后和危险因素。
Ann Hematol. 2021 Feb;100(2):505-516. doi: 10.1007/s00277-020-04380-0. Epub 2021 Jan 2.
7
Central nervous system (CNS) relapse following chemotherapy of WF rat acute myelogenous leukemia: a model for human CNS leukemia.
J Natl Cancer Inst. 1977 Apr;58(4):1139-46. doi: 10.1093/jnci/58.4.1139.
8
Factors associated with risk of central nervous system relapse in patients with non-core binding factor acute myeloid leukemia.非核心结合因子急性髓系白血病患者中枢神经系统复发风险的相关因素。
Am J Hematol. 2017 Sep;92(9):924-928. doi: 10.1002/ajh.24799. Epub 2017 Jul 19.
9
The safety and efficacy of the re-administration of gilteritinib in a patient with FLT3-mutated R/R AML with CNS relapse: a case report.吉瑞替尼再次给药治疗伴有中枢神经系统复发的FLT3突变复发/难治性急性髓系白血病患者的安全性和有效性：一例病例报告
Front Oncol. 2024 Jul 2;14:1402970. doi: 10.3389/fonc.2024.1402970. eCollection 2024.
10
Central Nervous System Prophylaxis and Treatment in Acute Leukemias.中枢神经系统预防和急性白血病治疗。
Curr Treat Options Oncol. 2022 Dec;23(12):1829-1844. doi: 10.1007/s11864-022-01032-5. Epub 2022 Dec 13.

引用本文的文献

1
Customizing delivery nano-vehicles for precise brain tumor therapy.定制用于精确脑肿瘤治疗的递药纳米载体。
J Nanobiotechnology. 2023 Jan 28;21(1):32. doi: 10.1186/s12951-023-01775-9.
2
Cytokines: Can Cancer Get the Message?细胞因子：癌症能收到信号吗？
Cancers (Basel). 2022 Apr 27;14(9):2178. doi: 10.3390/cancers14092178.

本文引用的文献

1
Prognosis and risk factors for central nervous system relapse after allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia.异基因造血干细胞移植后急性髓系白血病中枢神经系统复发的预后和危险因素。
Ann Hematol. 2021 Feb;100(2):505-516. doi: 10.1007/s00277-020-04380-0. Epub 2021 Jan 2.
2
CAR-T Cell Therapy for Acute Lymphoblastic Leukemia: Transforming the Treatment of Relapsed and Refractory Disease.嵌合抗原受体T细胞疗法治疗急性淋巴细胞白血病：改变复发难治性疾病的治疗方式
Curr Hematol Malig Rep. 2018 Oct;13(5):396-406. doi: 10.1007/s11899-018-0470-x.
3
Central nervous system involvement in acute lymphoblastic leukemia is mediated by vascular endothelial growth factor.
中枢神经系统在急性淋巴细胞白血病中的参与是由血管内皮生长因子介导的。
Blood. 2017 Aug 3;130(5):643-654. doi: 10.1182/blood-2017-03-769315. Epub 2017 May 26.
4
Managing CNS disease in adults with acute lymphoblastic leukemia.成人急性淋巴细胞白血病中枢神经系统疾病的管理
Leuk Lymphoma. 2018 Jan;59(1):3-13. doi: 10.1080/10428194.2017.1326597. Epub 2017 May 23.
5
Symptomatic central nervous system involvement in adult patients with acute myeloid leukemia.成年急性髓系白血病患者的有症状中枢神经系统受累情况
Cancer Manag Res. 2017 Mar 29;9:97-102. doi: 10.2147/CMAR.S125259. eCollection 2017.
6
Extramedullary Relapse of Acute Myeloid and Lymphoid Leukemia in Children: A Retrospective Analysis.儿童急性髓系白血病和急性淋巴细胞白血病的髓外复发：一项回顾性分析
Iran J Pediatr. 2016 May 28;26(3):e1711. doi: 10.5812/ijp.1711. eCollection 2016 Jun.
7
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial.用于治疗儿童和青年急性淋巴细胞白血病的表达CD19嵌合抗原受体的T细胞：一项1期剂量递增试验
Lancet. 2015 Feb 7;385(9967):517-528. doi: 10.1016/S0140-6736(14)61403-3. Epub 2014 Oct 13.
8
Expression and significance of vascular endothelial growth factor A and C in leukemia central nervous system metastasis.血管内皮生长因子 A 和 C 在白血病中枢神经系统转移中的表达及意义。
Leuk Res. 2013 Apr;37(4):359-66. doi: 10.1016/j.leukres.2012.10.008. Epub 2012 Nov 6.
9
Addition of bevacizumab to chemotherapy in acute myeloid leukemia at older age: a randomized phase 2 trial of the Dutch-Belgian Cooperative Trial Group for Hemato-Oncology (HOVON) and the Swiss Group for Clinical Cancer Research (SAKK).在老年急性髓系白血病中添加贝伐珠单抗联合化疗：荷兰-比利时血液肿瘤协作组（HOVON）和瑞士临床癌症研究组（SAKK）的一项随机 2 期试验。
Blood. 2012 Dec 6;120(24):4706-11. doi: 10.1182/blood-2012-04-420596. Epub 2012 Oct 9.
10
Cytogenetic profile of patients with acute myeloid leukemia and central nervous system disease.急性髓系白血病伴中枢神经系统疾病患者的细胞遗传学特征。
Cancer. 2012 Jan 1;118(1):112-7. doi: 10.1002/cncr.26253. Epub 2011 Jun 20.