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3型自身免疫性多腺体综合征:一例罕见表现的病例报告及文献综述

Autoimmune polyglandular syndrome type 3: A case report of an unusual presentation and literature review.

作者信息

Apolinario Michael, Brussels Aaron, Cook Curtiss B, Yang Shaun

机构信息

Department of Internal Medicine Mayo Clinic College of Medicine and Science Scottsdale Arizona USA.

Department of Anesthesiology and Perioperative Medicine Mayo Clinic College of Medicine and Science Scottsdale Arizona USA.

出版信息

Clin Case Rep. 2022 Feb 4;10(2):e05391. doi: 10.1002/ccr3.5391. eCollection 2022 Feb.

Abstract

Autoimmune polyglandular syndromes (APS) are rare disorders characterized by auto-destruction of endocrine and non-endocrine organs by organ-specific antibody-directed T-lymphocytic infiltration. This case highlights a 29-year-old Caucasian man with vitiligo found to have significant neurological abnormalities in the setting of newly diagnosed pernicious anemia and thyroid autoimmune disease.

摘要

自身免疫性多内分泌腺综合征(APS)是一种罕见的疾病,其特征是器官特异性抗体介导的T淋巴细胞浸润导致内分泌和非内分泌器官的自身破坏。本病例重点介绍了一名29岁的白种男性,患有白癜风,在新诊断为恶性贫血和甲状腺自身免疫性疾病的情况下,发现有明显的神经学异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c581/8815091/fc9a616d94bc/CCR3-10-e05391-g001.jpg

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