Reid W J
Food Addit Contam. 1986 Jan-Mar;3(1):1-42. doi: 10.1080/02652038609373562.
This report presents a review of the literature on the extraction and clean-up procedures used prior to the analysis, by mass spectrometry, of organic contaminants and toxicants in foods and food-related materials. It includes a brief description of the uses of a mass spectrometer and shows how the mode of operation of the machine can influence the amount of clean-up necessary before a sample is presented for analysis. The review covers a variety of contaminants of different compound types in a wide range of foods and not only discusses sample preparation techniques that have been used for contaminant analysis by mass spectrometry but also considers some that could be used. The most commonly used techniques involve solvent extraction followed by a clean-up using liquid-liquid partition or column chromatography or both, although a number of newer methods being evolved are moving towards the ideal of a single-step extraction and clean-up process.
本报告综述了有关食品及食品相关材料中有机污染物和有毒物质在质谱分析前的提取和净化程序的文献。报告简要介绍了质谱仪的用途，并展示了仪器的操作模式如何影响在样品进行分析前所需的净化量。该综述涵盖了各种食品中不同化合物类型的多种污染物，不仅讨论了已用于通过质谱分析污染物的样品制备技术，还考虑了一些可能会用到的技术。最常用的技术包括溶剂萃取，然后通过液-液分配或柱色谱法或两者结合进行净化，不过正在发展的一些新方法正朝着一步提取和净化过程的理想目标迈进。
