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[长春胺治疗初发性脑血管机能不全。828例多中心研究]

[Treatment of initial cerebrovascular insufficiency with vincamine. Polycentric research on 828 cases].

出版信息

Minerva Med. 1978 Jun 23;69(31):2095-113.

PMID:351463
Abstract

The effect of vincamine on initial cerebrovascular insufficiency was examined by investigation of data relating to 828 patients from 11 centres. Most had received 6 tablets/day for 30 days. The method selected in gathering the data and their processing is described. Classic symptoms of initial insufficiency were considered after 7, 14, 21 and 30 days and evaluated along with a "seriousness" index relating to the symptomatology as a whole. The results pointed to continuous improvement in individual symptoms and overall from the outset of treatment, eventually leading to high remission percentages. Tolerance was generally good and very few cases of side-effects were reported.

摘要

通过对来自11个中心的828例患者的数据进行调查,研究了长春胺对早期脑血管供血不足的疗效。大多数患者每天服用6片,持续30天。文中描述了收集数据和处理数据所选用的方法。在第7、14、21和30天对早期供血不足的典型症状进行评估,并结合与整体症状学相关的“严重程度”指数进行评价。结果表明,从治疗开始,个体症状和整体症状均持续改善,最终缓解率很高。耐受性总体良好,报告的副作用病例很少。

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