Douglas V I, Barr R G, O'Neill M E, Britton B G
J Child Psychol Psychiatry. 1986 Mar;27(2):191-211. doi: 10.1111/j.1469-7610.1986.tb02330.x.
Sixteen children meeting diagnostic criteria for Attention Deficit Disorder with Hyperactivity (ADD-H) were tested on methylphenidate (0.3 mg/kg) and placebo on cognitive, learning, academic and behavioral measures in a double-blind study. Assessments were carried out in the laboratory and in the children's regular classrooms. Results indicate methylphenidate-induced improvements on a majority of the measures. Drug-induced changes reflected increased output, accuracy and efficiency and improved learning acquisition. There was also evidence of increased effort and self-correcting behaviours. It is argued that reviewers have underestimated the potential of stimulants to improve the performance of ADD-H children on academic, learning and cognitive tasks.
在一项双盲研究中，对16名符合多动性注意力缺陷障碍（ADD-H）诊断标准的儿童，就认知、学习、学业及行为指标，分别使用哌甲酯（0.3毫克/千克）和安慰剂进行了测试。评估在实验室及儿童的常规教室中进行。结果表明，哌甲酯使大部分指标得到改善。药物引起的变化反映出产出增加、准确性提高、效率提升以及学习获得改善。还有证据表明努力程度和自我纠正行为有所增加。有人认为，评审人员低估了兴奋剂对改善ADD-H儿童在学业、学习和认知任务上表现的潜力。
