Brodovsky S, Dagan R, Ben-Bassatt M
J Dermatol Surg Oncol. 1986 Apr;12(4):386-8. doi: 10.1111/j.1524-4725.1986.tb01924.x.
Various methods have been used for managing split-thickness skin graft donor sites. Open and closed techniques have been suggested by various authors with the purpose of achieving smooth and rapid healing of the wound. There is growing evidence to suggest that the site and quality of the healing is improved when the wound is protected from dehydration and further mechanical trauma. A recent method is the spraying of Nobecutane Spray on the donor site. Nobecutane sprayed on a wound forms a plastic film which serves as a dressing material. It contains specially modified acrylic resin in an organic solvent (ethyl acetate) and TMTD (tetramethylthiuram disulphide) which is strongly bactericidal and fungicidal. We employed this method on 50 patients and found it to be effective in achieving rapid and painless healing. The dressing is transparent, permits easy follow-up of healing in the donor site, protects the wound against infection, and does not inconvenience the patient. The treatment is simple, economical, and does not require special skills. The dressing peels off spontaneously after epidermal regeneration of the wound is completed. No complications or allergic reaction were observed with this treatment.
处理中厚皮片供皮区有多种方法。不同作者提出了开放和封闭技术,目的是实现伤口的顺利快速愈合。越来越多的证据表明,当伤口免受脱水和进一步机械创伤时,愈合部位和质量会得到改善。一种最新的方法是在供皮区喷洒诺必行喷雾剂。喷在伤口上的诺必行形成一层塑料薄膜,可作为敷料材料。它在有机溶剂(乙酸乙酯)中含有特殊改性的丙烯酸树脂和具有强力杀菌和杀真菌作用的二硫化四甲基秋兰姆(TMTD)。我们对50例患者采用了这种方法,发现它能有效实现快速且无痛的愈合。该敷料是透明的,便于对供皮区的愈合情况进行随访,能保护伤口免受感染,且不会给患者带来不便。治疗方法简单、经济,不需要特殊技能。伤口表皮再生完成后,敷料会自动脱落。采用这种治疗方法未观察到并发症或过敏反应。