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帕金森病患者床移动能力受损的决定因素:髋关节肌肉力量和运动症状的影响。

Determinants of impaired bed mobility in Parkinson's disease: Impact of hip muscle strength and motor symptoms.

机构信息

Center for Information and Neural Networks (CiNet), Advanced ICT Research Institute, National Institute of Information and Communications Technology (NICT), Suita, Japan.

Osaka University Graduate School of Medicine, Suita, Japan.

出版信息

NeuroRehabilitation. 2022;50(4):445-452. doi: 10.3233/NRE-210301.

DOI:10.3233/NRE-210301
PMID:35147569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9277679/
Abstract

BACKGROUND

Although most patients with Parkinson's disease (PD) present difficulties of bed mobility, the contributing factors to impaired bed mobility in PD are unknown.

OBJECTIVE

To compare bed mobility and muscle strength between PD patients and healthy controls, and investigate the determinants of bed mobility in PD.

METHODS

Sixteen patients with PD and ten age- and sex-matched healthy controls (HC) were enrolled. Time and pattern to get out of bed to their preferred side at usual speed, muscle torque in lower extremities and motor symptom burden were also measured.

RESULTS

PD exhibited significantly slower speed in bed mobility and lower torque in the hip adductor/abductor/flexor muscle than HC. Slower movement time in PD was correlated with weaker hip adductor torque on the more affected side (Rs = -0.56, p < 0.05) and with higher score in arm rigidity both sides (Rs≥0.79, p < 0.01). There were no significant differences between the categorised movement patterns and movement time in PD (p = 0.31).

CONCLUSIONS

Reduced hip adductors torque and severe arm rigidity are associated with slowness of getting out of bed, implying that these components could be used as targets for rehabilitation practice to improve bed mobility in PD.

摘要

背景

尽管大多数帕金森病(PD)患者存在卧床移动困难,但导致 PD 患者卧床移动受损的因素尚不清楚。

目的

比较 PD 患者与健康对照者的卧床移动能力和肌肉力量,并探讨 PD 患者卧床移动能力的决定因素。

方法

纳入 16 例 PD 患者和 10 名年龄和性别匹配的健康对照者(HC)。还测量了以通常速度向惯用侧下床的时间和模式、下肢肌肉扭矩和运动症状负担。

结果

PD 患者的卧床移动速度明显较慢,髋关节内收肌/外展肌/屈肌的扭矩也较低。PD 患者的运动时间较慢与患侧较弱的髋关节内收肌扭矩(Rs=-0.56,p<0.05)和双侧手臂僵硬评分较高(Rs≥0.79,p<0.01)相关。PD 患者的分类运动模式和运动时间之间无显著差异(p=0.31)。

结论

髋关节内收肌扭矩降低和手臂僵硬严重与下床速度减慢相关,这表明这些因素可作为康复实践的目标,以改善 PD 患者的卧床移动能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0737/9277679/39bbe8d5199a/nre-50-nre210301-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0737/9277679/39bbe8d5199a/nre-50-nre210301-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0737/9277679/39bbe8d5199a/nre-50-nre210301-g001.jpg

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本文引用的文献

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Validation and Reliability of the Japanese Version of the Modified Parkinson Activity Scale (M-PAS).改良帕金森活动量表(M-PAS)日语版的效度与信度
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Outcome Measures for Evaluating the Effect of a Multidisciplinary Intervention on Axial Symptoms of Parkinson's Disease.评估多学科干预对帕金森病轴向症状影响的结局指标
Front Neurol. 2020 May 12;11:328. doi: 10.3389/fneur.2020.00328. eCollection 2020.
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Tossing and Turning in Bed: Nocturnal Movements in Parkinson's Disease.
帕金森病患者夜间活动能力受损:一项系统评价。
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Technological evaluation of strategies to get out of bed by people with Parkinson's disease: Insights from multisite wearable sensors.帕金森病患者起床策略的技术评估:来自多地点可穿戴传感器的见解
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辗转反侧:帕金森病的夜间运动。
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Evolution of prodromal Parkinson's disease and dementia with Lewy bodies: a prospective study.前驱期帕金森病和路易体痴呆的演变:一项前瞻性研究。
Brain. 2019 Jul 1;142(7):2051-2067. doi: 10.1093/brain/awz111.
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Axial symptoms predict mortality in patients with Parkinson disease and subthalamic stimulation.轴向症状预测帕金森病患者和丘脑底核刺激后的死亡率。
Neurology. 2019 May 28;92(22):e2559-e2570. doi: 10.1212/WNL.0000000000007562. Epub 2019 May 1.
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Analysis of trunk rolling in Parkinson's disease patients using a mattress mobility detection system.使用床垫活动检测系统分析帕金森病患者的躯干滚动。
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Impaired bed mobility: quantitative torque analysis with axial inertial sensors.床上活动能力受损:使用轴向惯性传感器进行定量扭矩分析。
Neurodegener Dis Manag. 2017 Aug;7(4):235-243. doi: 10.2217/nmt-2017-0016. Epub 2017 Aug 30.
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Capturing nighttime symptoms in Parkinson disease: Technical development and experimental verification of inertial sensors for nocturnal hypokinesia.捕捉帕金森病的夜间症状:用于夜间运动迟缓的惯性传感器的技术开发与实验验证
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How well do Parkinson's disease patients turn in bed? Quantitative analysis of nocturnal hypokinesia using multisite wearable inertial sensors.帕金森病患者在床上翻身情况如何?使用多部位可穿戴惯性传感器对夜间运动迟缓进行定量分析。
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