Taniguchi Seira, Nakata Yoko, Inoue Michiko, Marumoto Kohei
Center for Information and Neural Networks, Advanced ICT Research Institute, NICT, Osaka, Japan.
Department of Physical Medicine and Rehabilitation, Hyogo Prefectural Rehabilitation Hospital at Nishi-Harima, Hyogo, Japan.
Prog Rehabil Med. 2021 Dec 22;6:20210051. doi: 10.2490/prm.20210051. eCollection 2021.
The Modified Parkinson Activity Scale (M-PAS) is used to identify the most important activity limitations in patients with Parkinson's disease. We developed a Japanese version of the M-PAS and evaluated its reliability and validity.
Twenty-five patients with Parkinson's disease (median age 71 years old, range 58-83) were enrolled, and two raters used the Japanese version of M-PAS to assess the subjects. The inter-rater reliability was evaluated using Cohen's weighted kappa coefficient for the total score and three domain scores; systematic error was investigated using Bland-Altman analysis. Concurrent validity of the Japanese M-PAS was measured using Spearman's rank correlation coefficients.
Cohen's kappa coefficients for the total score and the three domain scores were in the range 0.81-0.98, and 95% confidence intervals included zero for each item, suggesting excellent agreement and no systematic errors. The scores of the Japanese version of M-PAS were significantly correlated with the scores of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale Part II (Spearman's rho=-0.56, P <0.01) and Part III (Spearman's rho=-0.32, P <0.01). The percentage of patients with the highest and the lowest scores in the Japanese version of M-PAS suggested no ceiling or floor effects.
The Japanese version of M-PAS showed excellent inter-rater reliability and good concurrent validity without ceiling or floor effects.
改良帕金森活动量表（M-PAS）用于识别帕金森病患者最重要的活动受限情况。我们开发了M-PAS的日语版本，并评估了其信度和效度。
纳入25例帕金森病患者（中位年龄71岁，范围58 - 83岁），两名评估者使用M-PAS日语版本对受试者进行评估。使用Cohen加权kappa系数评估总分及三个领域得分的评估者间信度；使用Bland-Altman分析研究系统误差。使用Spearman等级相关系数测量M-PAS日语版本的同时效度。
总分及三个领域得分的Cohen kappa系数在0.81 - 0.98范围内，各项目的95%置信区间包含零，表明一致性良好且无系统误差。M-PAS日语版本的得分与运动障碍协会统一帕金森病评定量表第二部分（Spearman相关系数=-0.56，P<0.01）和第三部分（Spearman相关系数=-0.32，P<0.01）的得分显著相关。M-PAS日语版本中得分最高和最低的患者百分比表明无天花板效应或地板效应。
M-PAS日语版本显示出良好的评估者间信度和良好的同时效度，且无天花板效应或地板效应。
