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贝林格顿和诺姆-杰克贝伐单抗注射后眼内硅油滴的频率和症状。

Frequency and Symptoms of Intravitreal Silicone Oil Droplets Following Becton Dickinson and Norm-Ject Bevacizumab Injections.

出版信息

Ophthalmic Surg Lasers Imaging Retina. 2022 Feb;53(2):108-112. doi: 10.3928/23258160-20220124-03. Epub 2022 Feb 1.

Abstract

BACKGROUND AND OBJECTIVE

To determine silicone oil droplet frequency and symptomatic impact in patients injected with Norm-Ject (NJ) and/or Becton Dickinson (BD) intravitreal bevacizumab.

PATIENTS AND METHODS

This was a retrospective cohort study of 426 patients with prior bevacizumab injection(s). Symptomatic floaters questionnaire responses were compiled and statistical analysis was performed using Fisher's exact t test with 95% CI calculated via the modified Wald method.

RESULTS

Patients who received BD intravitreal bevacizumab showed more droplets (67.2%) than those who received NJ intravitreal bevacizumab (7.8%), and droplets increased with injection quantity. However, the symptomatic patients reporting new floaters were similar (NJ: 39.22%, BD: 39.47%). .

摘要

背景和目的

确定注射诺华(Norm-Ject,NJ)和/或贝克顿·迪金森(Becton Dickinson,BD)玻璃体内贝伐单抗的患者硅油滴频率和症状影响。

患者和方法

这是一项回顾性队列研究,纳入了 426 例先前接受过贝伐单抗注射的患者。对有症状的飞蚊症问卷应答进行了汇编,并使用 Fisher 确切检验进行了统计学分析,95%置信区间通过修正 Wald 方法计算。

结果

接受 BD 玻璃体内贝伐单抗注射的患者出现硅油滴的比例(67.2%)高于接受 NJ 玻璃体内贝伐单抗注射的患者(7.8%),且硅油滴的数量随注射次数增加而增加。然而,报告出现新飞蚊症的症状性患者比例相似(NJ:39.22%,BD:39.47%)。

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