Department of Psychology, Lancaster University, Lancaster LA1 4YF, United Kingdom; Brain and Cognition Research Centre, University of Toulouse Paul Sabatier, Toulouse, France; Brain and Cognition Research Centre, CNRS, UMR-5549, Toulouse, France.
Department of Psychology, Lancaster University, Lancaster LA1 4YF, United Kingdom; Manchester Centre for Audiology and Deafness, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, United Kingdom.
Hear Res. 2022 Apr;417:108456. doi: 10.1016/j.heares.2022.108456. Epub 2022 Jan 31.
There is a large amount of variability in performance in masked-speech reception tasks, as well as in psychophysical auditory temporal processing tasks, between listeners with normal or relatively normal low-frequency hearing. In this study we used a cross-sectional dataset collected on 102 listeners (34 young, 34 middle-aged, 34 older) to assess whether variance in these tasks could be explained by variance in subcortical electrophysiological measures of auditory function (auditory brainstem responses and frequency following responses), and whether variance in speech-reception performance could be explained by variance in auditory temporal processing tasks. The potential confounding effect of high-frequency sensitivity was strictly controlled for by using highpass masking noise. Because each high-level construct (masked-speech reception, auditory temporal processing, and subcortical electrophysiological function) was indexed by several variables, we used principal component analyses to reduce the dimensionality of the dataset. Multiple-regression models were then used to assess the associations between the extracted principal components while controlling for a range of possible confounders including age and audiometric thresholds. We found that masked-speech reception was credibly associated with psychophysical auditory temporal processing abilities. No credible associations were found between masked-speech reception and electrophysiological measures of subcortical auditory function, or between psychophysical measures of auditory temporal processing and electrophysiological measures of subcortical auditory function. These results suggest that either the electrophysiological measures of subcortical auditory function used were not sufficiently sensitive to the subcortical neural processes limiting performance in the speech-reception and psychophysical auditory temporal-processing tasks, or that variance in these tasks is largely unrelated to variance in subcortical neural processes in listeners with near-normal hearing.
在有正常或相对正常低频听力的听众中,在掩蔽语音接收任务以及心理物理听觉时程处理任务中的表现存在大量的可变性。在这项研究中,我们使用了在 102 名听众(34 名年轻人,34 名中年人,34 名老年人)中收集的横断面数据集,评估这些任务中的方差是否可以用听觉功能的皮质下电生理测量(听觉脑干反应和频率跟随反应)的方差来解释,以及言语接收性能的方差是否可以用听觉时程处理任务的方差来解释。通过使用高通掩蔽噪声严格控制高频灵敏度的混杂效应。由于每个高级结构(掩蔽语音接收、听觉时程处理和皮质下电生理功能)都由多个变量表示,因此我们使用主成分分析来降低数据集的维度。然后使用多元回归模型来评估在控制年龄和听力阈值等一系列可能混杂因素的情况下,提取的主成分之间的关联。我们发现,掩蔽语音接收与心理物理听觉时程处理能力有可信的关联。在掩蔽语音接收和皮质下听觉功能的电生理测量之间,或在心理物理听觉时程处理测量和皮质下听觉功能的电生理测量之间,没有发现可信的关联。这些结果表明,要么使用的皮质下听觉功能的电生理测量对限制言语接收和心理物理听觉时程处理任务中表现的皮质下神经过程不够敏感,要么这些任务中的方差与具有接近正常听力的听众的皮质下神经过程中的方差基本无关。