Cunha Sara C, Menezes-Sousa Dhoone, Mello Flávia V, Miranda Joyce A T, Fogaca Fabiola H S, Alonso Mariana B, Torres João Paulo M, Fernandes José O
LAQV-REQUIMTE, Laboratory of Bromatology and Hydrology, Faculty of Pharmacy, University of Porto, Rua Jorge de Viterbo Ferreira 228, 4050-313, Porto, Portugal.
LAQV-REQUIMTE, Laboratory of Bromatology and Hydrology, Faculty of Pharmacy, University of Porto, Rua Jorge de Viterbo Ferreira 228, 4050-313, Porto, Portugal; Micropollutants Laboratory Jan Japenga, Instituto de Biofisica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro. Av. Carlos Chagas Filho, 373 - CCS - Bl. G, 21941-902, Rio de Janeiro, RJ, Brazil.
Environ Res. 2022 Jul;210:112886. doi: 10.1016/j.envres.2022.112886. Epub 2022 Feb 9.
Currently, the presence of endocrine disrupting chemicals (EDCs) in the marine environment pose а potential risk to both wildlife and human health. The occurrence of EDCs in seafood depends of several factors such as source and amounts of EDCs that reach the aquatic environment, physicochemical features of EDCs, and its accumulation in trophic chain. This review highlights the occurrence and distribution of EDCs along the seafood in the last 6 years. The following EDCs were included in this review: brominated flame retardants (PBDEs, PBBs, HBCDDs, TBBPA, and novel flame retardants); pharmaceuticals (paracetamol, ibuprofen, diclofenac, carbamazepine), bisphenols, hormones, personal care products (Musk and UV Filters), and pesticides (organochlorides, organophosphates, and pyrethroids). Some of them were found above the threshold that may cause negative effects on human, animal, and environmental health. More control in some countries, as well as new legislation and inspection over the purchase, sale, use, and production of these compounds, are urgently needed. This review provides data to support risk assessment and raises critical gaps to stimulate and improve future research.
目前,海洋环境中存在的内分泌干扰化学物质(EDCs)对野生动物和人类健康都构成了潜在风险。海产品中EDCs的出现取决于几个因素,如进入水生环境的EDCs的来源和数量、EDCs的物理化学特性及其在营养链中的积累。本综述重点介绍了过去6年中EDCs在海产品中的出现情况和分布。本综述涵盖了以下EDCs:溴化阻燃剂(多溴二苯醚、多溴联苯、六溴环十二烷、四溴双酚A和新型阻燃剂);药物(对乙酰氨基酚、布洛芬、双氯芬酸、卡马西平)、双酚、激素、个人护理产品(麝香和紫外线过滤剂)以及农药(有机氯、有机磷和拟除虫菊酯)。其中一些物质的含量超过了可能对人类、动物和环境健康造成负面影响的阈值。一些国家迫切需要加强管控,以及出台新的法律法规并加强对这些化合物的采购、销售、使用和生产的监管。本综述提供了支持风险评估的数据,并指出了关键差距,以促进和改进未来的研究。