Department of Diagnostic Radiology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China.
MR Research, GE Healthcare, Beijing 100076, China.
Trends Cardiovasc Med. 2023 Aug;33(6):346-354. doi: 10.1016/j.tcm.2022.02.002. Epub 2022 Feb 10.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that primarily affects young women. Myocardial involvement in SLE frequently occurs and it is rather challenging to make the diagnosis in current clinical settings, mainly due to the extensive clinical presentation of signs and symptoms. As a noninvasive imaging reference in diagnosing cardiomyopathy and myocarditis, cardiovascular magnetic resonance (CMR) imaging can provide new insight into myocardial abnormalities including inflammation, fibrosis, and microcirculation. Therefore, the main aim of this work was to systematically review the pathology, clinical features, and diagnosis, while illustrating the clinical role of CMR on myocardial involvement of SLE.
系统性红斑狼疮（SLE）是一种慢性自身免疫性疾病，主要影响年轻女性。SLE 常伴有心肌受累，目前在临床环境中诊断较为困难，主要是由于其临床表现广泛且多样。心血管磁共振（CMR）成像作为一种诊断心肌病和心肌炎的无创影像学参考方法，可以为包括炎症、纤维化和微循环在内的心肌异常提供新的见解。因此，本研究的主要目的是系统地综述 SLE 心肌受累的病理学、临床特征和诊断，并阐述 CMR 在其中的临床作用。
