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东南亚地区变应原谱、致敏模式及变应性鼻炎的特征

Characteristics of allergen profile, sensitization patterns and Allergic Rhinitis in SouthEast Asia.

作者信息

Pham Duy Le, Trinh Tu Hoang Kim, Le Kieu Minh, Pawankar Ruby

机构信息

Faculty of Medicine.

Center for Molecular Biomedicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.

出版信息

Curr Opin Allergy Clin Immunol. 2022 Apr 1;22(2):137-142. doi: 10.1097/ACI.0000000000000814.

Abstract

PURPOSE OF REVIEW

To highlight the characteristics of allergic rhinitis, local allergic rhinitis (LAR), and importance of allergens in Southeast Asian countries.

RECENT FINDINGS

The Asia-Pacific region is very diverse with disparities in the epidemiological data between countries as well as in the unmet needs. The prevalence of allergic rhinitis has markedly increased in the past decades, with a high variation between countries, ranging from 4.5--80.3%. In terms of LAR, the reported prevalence in Southeast Asia is similar to that of other Asian countries (3.7-24.9%) but lower than that in western countries. House dust mites, cockroach, pollens, and molds are major allergens that are known triggers for of allergic rhinitis in this region, whereas the association with helminth infection requires further investigation.

SUMMARY

There are gaps and high variation between countries in Southeast Asia regarding the prevalence of allergic rhinitis and LAR. Further studies are needed to fully elucidate the association between allergens and allergic rhinitis in Southeast Asia.

摘要

综述目的

强调东南亚国家变应性鼻炎、局部变应性鼻炎(LAR)的特点以及变应原的重要性。

最新发现

亚太地区非常多样化,各国之间的流行病学数据以及未满足的需求存在差异。在过去几十年中,变应性鼻炎的患病率显著增加,各国之间差异很大,范围从4.5%-80.3%。就LAR而言,东南亚报告的患病率与其他亚洲国家相似(3.7%-24.9%),但低于西方国家。屋尘螨、蟑螂、花粉和霉菌是该地区已知的变应性鼻炎主要触发变应原,而与蠕虫感染的关联需要进一步研究。

总结

东南亚国家在变应性鼻炎和LAR的患病率方面存在差距且差异很大。需要进一步研究以充分阐明东南亚变应原与变应性鼻炎之间的关联。

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