Kuner E H, Keller H
Orthopade. 1986 Feb;15(1):16-21.
A well-organized bone bank for cryoconservation is a proven and safe procedure, which is best suitable for emergency surgery. If the indication is correct and donor selection carefully proved, it is an efficient procedure without great problems. For donor selection, the history of the patient, a clinical examination and serological tests are very important, in addition to an aseptic procurement and continuous maintenance of temperature in the freezer. The freezer temperature must be kept below the eutectic point of bone (-28 degrees C). At this temperature all of the individual bone tissue structures are frozen, and bone can be preserved for 1 year in this way. We prefer a cryoconservation at -39/49 degrees C. In the Department of Traumatology of the University in Freiburg, in the last 16 years more than 1000 homologous bone grafts have been performed. Although in the first weeks consolidation is delayed, the rate of complications after bone transplantations is low. The great advantage is the availability of homologous (allogenous) cancellous bone and cortical bone chips at any time, especially for the treatment of polytraumatized patients.
一个组织完善的用于低温保存的骨库是一种经过验证的安全程序，非常适合急诊手术。如果适应证正确且供体选择经过仔细验证，那么它是一种高效的程序，不会出现大的问题。对于供体选择，除了无菌获取和在冷冻库中持续保持温度外，患者的病史、临床检查和血清学检测非常重要。冷冻库温度必须保持在骨的共晶点（-28摄氏度）以下。在此温度下，所有单个骨组织结构都会被冻结，骨可以通过这种方式保存1年。我们更倾向于在-39/49摄氏度下进行低温保存。在弗莱堡大学创伤科，过去16年里已经进行了1000多次同种异体骨移植。尽管在最初几周骨愈合会延迟，但骨移植后的并发症发生率较低。其最大优势在于随时都能获得同种异体（异体）松质骨和皮质骨碎片，尤其适用于多发伤患者的治疗。
