Radiation Oncology Department, CHRU Morvan, 2, avenue Foch, 29609 Brest cedex, France.
LaTIM, INSERM, UMR 1101, University of Brest, 29200, Brest, France.
Cancer Radiother. 2022 Jun;26(4):616-621. doi: 10.1016/j.canrad.2021.10.008. Epub 2022 Feb 10.
Radiotherapy remains an important treatment modality for patients with chest malignancies; this is particularly true in patients with breast cancer and Hodgkin lymphoma as well as lung, esophageal, and other mediastinal tumors. More than half of patients with these conditions receive radiotherapy at some point. With the development of new treatment modalities, we are witnessing an improvement of overall survival requiring carefully watching of acute and chronic toxicity of radiation therapy. The challenge is not to ignore radiotherapy's side effects in order to explore and prevent them in the future. Strategies for optimizing thoracic radiotherapy and the advent of innovative techniques may represent an encouraging way to decrease thoracic toxicities. We reviewed the literature to identify these cases of toxicity, which are sometimes forgotten, and others, which have recently been described but remain poorly known.
放射治疗仍然是胸部恶性肿瘤患者的重要治疗方式；这在乳腺癌和霍奇金淋巴瘤患者以及肺癌、食管癌和其他纵隔肿瘤患者中尤其如此。超过一半的此类患者在某个阶段会接受放射治疗。随着新治疗方式的发展，我们见证了整体生存率的提高，这需要仔细观察放射治疗的急性和慢性毒性。挑战在于，为了将来探索和预防放射治疗的副作用，我们不能忽视这些副作用。优化胸部放射治疗的策略和创新技术的出现可能是减少胸部毒性的一种有希望的方法。我们查阅了文献，以确定这些有时被遗忘的毒性病例，以及最近描述但仍知之甚少的其他毒性病例。
