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一种研究细菌对有毒染料进行酶促降解的综合方法。

An Integrative Approach to Study Bacterial Enzymatic Degradation of Toxic Dyes.

作者信息

Mishra Arti, Takkar Simran, Joshi Naveen Chandra, Shukla Smriti, Shukla Kartikeya, Singh Anamika, Manikonda Anusha, Varma Ajit

机构信息

Amity Institute of Microbial Technology, Amity University, Noida, India.

Amity Institute of Environmental Toxicology, Safety and Management, Amity University, Noida, India.

出版信息

Front Microbiol. 2022 Jan 28;12:802544. doi: 10.3389/fmicb.2021.802544. eCollection 2021.

Abstract

Synthetic dyes pose a large threat to the environment and consequently to human health. Various dyes are used in textile, cosmetics, and pharmaceutical industries, and are released into the environment without any treatment, thus adversely affecting both the environment and neighboring human populations. Several existing physical and chemical methods for dye degradation are effective but have many drawbacks. Biological methods over the years have gained importance in the decolorization and degradation of dye and have also overcome the disadvantages of physiochemical methods. Furthermore, biological methods are eco-friendly and lead to complete decolorization. The mechanism of decolorization and degradation by several bacterial enzymes are discussed in detail. For the identification of ecologically sustainable strains and their application at the field level, we have focused on bioaugmentation aspects. Furthermore, studies such as molecular docking of bacterial enzymes with dyes can give a new insight into biological studies and provide an easy way to understand the interaction at the molecular level. This review mainly focuses on an integrative approach and its importance for the effective treatment and decolorization of dyes.

摘要

合成染料对环境进而对人类健康构成巨大威胁。各种染料被用于纺织、化妆品和制药行业,未经任何处理就被排放到环境中,从而对环境和周边人群产生不利影响。现有的几种物理和化学染料降解方法虽有效,但存在诸多缺点。多年来,生物方法在染料脱色和降解方面变得越来越重要,并且克服了物理化学方法的缺点。此外,生物方法对生态环境友好,能实现完全脱色。本文详细讨论了几种细菌酶的脱色和降解机制。为了鉴定具有生态可持续性的菌株及其在实际应用中的效果,我们重点关注了生物强化方面。此外,诸如细菌酶与染料的分子对接等研究可以为生物学研究提供新的见解,并提供一种在分子水平上理解相互作用的简便方法。本综述主要关注一种综合方法及其对染料有效处理和脱色的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f05/8831545/e9269e52b4cb/fmicb-12-802544-g001.jpg

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