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咖啡因中毒:不受监管的非处方销售潜在致命补充剂。

Caffeine Intoxication: Unregulated, Over-the-Counter Sale of Potentially Deadly Supplements.

作者信息

Pina Cabral João, Sousa David L, Carvalho Catarina, Girao Adriana, Pacheco Mendes Adriano, Pina Rui

机构信息

Internal Medicine, Centro Hospitalar e Universitário de Coimbra, Coimbra, PRT.

Family Medicine, USF Novo Norte, ARS Norte, Arouca, PRT.

出版信息

Cureus. 2022 Jan 9;14(1):e21045. doi: 10.7759/cureus.21045. eCollection 2022 Jan.

Abstract

Caffeine is an integral part of beverages, food, and medications. Severe intoxication of caffeine is rare, and reports are even scarcer. However, over-the-counter, unregulated sale of performance-enhancing compounds, such as caffeine, turns high-dose consumption into a real concern. Severe intoxication may be fatal, usually by malignant cardiac arrhythmia. We report a case of a 23-year-old university student who accidentally consumed about 100 times the amount present in an expresso of anhydrous caffeine.

摘要

咖啡因是饮料、食品和药物中不可或缺的一部分。严重的咖啡因中毒很罕见,相关报道更是稀少。然而,像咖啡因这样的提高成绩的化合物在非处方、不受监管的情况下销售,使得高剂量摄入成为一个切实令人担忧的问题。严重中毒可能是致命的,通常是由恶性心律失常导致。我们报告一例23岁大学生的病例,该学生意外摄入了约为一杯特浓咖啡中无水咖啡因含量100倍的量。

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JACC Clin Electrophysiol. 2018 Apr;4(4):425-432. doi: 10.1016/j.jacep.2018.01.012.
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Dangerous mistake: an accidental caffeine overdose.危险错误:意外的咖啡因过量。
BMJ Case Rep. 2018 Jun 8;2018:bcr-2018-224185. doi: 10.1136/bcr-2018-224185.
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The Safety of Ingested Caffeine: A Comprehensive Review.摄入咖啡因的安全性:全面综述
Front Psychiatry. 2017 May 26;8:80. doi: 10.3389/fpsyt.2017.00080. eCollection 2017.
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Electrocardiogram Abnormalities of Caffeine Overdose.咖啡因过量的心电图异常
Circ Arrhythm Electrophysiol. 2016 Jul;9(7). doi: 10.1161/CIRCEP.115.003088.

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