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一例先前患有菊池-藤本病的女性狼疮性脑炎病例报告。

A Case Report of Lupus Cerebritis in a Female With Preceding Kikuchi-Fujimoto Disease.

作者信息

Al Barazanjy Hussein A, Alabdullah Ali R, Shabbir Azhar, Raheemah AlMalchi Mohammed Q, Hussein Ameer F

机构信息

Neurology, Al-Najaf Al-Ashraf Teaching Hospital, Al-Najaf, IRQ.

Neurology, Al-Najaf Al-Ashraf Teaching Hospital, Poiliclinico San Donato, Al-Najaf, IRQ.

出版信息

Cureus. 2025 Apr 19;17(4):e82594. doi: 10.7759/cureus.82594. eCollection 2025 Apr.

Abstract

A rare, benign, self-limiting illness known as Kikuchi-Fujimoto disease (KFD) is characterized by fever and lymphadenopathy in young females. Systemic lupus erythematosus (SLE), on the other hand, is a fairly prevalent autoimmune disease. Kikuchi disease is sometimes associated with SLE, with which it may coexist. To validate the diagnosis, the presence of necrotizing lymphadenitis is considered to be of significance. A positive anti-nuclear antibody (ANA) suggests a potential association with SLE or a relapse of the underlying condition. To avoid incorrect diagnosis and ineffective therapy, this clinical presentation requires a comprehensive evaluation. Steroids and immunological therapy are used to treat Kikuchi illness, which is a persistent and recurrent condition that usually requires supportive care. Early diagnosis of ominous disorders requires long-term surveillance.

摘要

一种罕见的、良性的、自限性疾病,称为菊池-藤本病(KFD),其特征为年轻女性出现发热和淋巴结病。另一方面,系统性红斑狼疮(SLE)是一种相当常见的自身免疫性疾病。菊池病有时与SLE相关,二者可能共存。为了确诊,坏死性淋巴结炎的存在被认为具有重要意义。抗核抗体(ANA)阳性提示可能与SLE有关或潜在病情复发。为避免误诊和无效治疗,这种临床表现需要全面评估。菊池病是一种持续且复发的疾病,通常需要支持性护理,治疗时使用类固醇和免疫疗法。对严重疾病的早期诊断需要长期监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7498/12088232/6582e28607a9/cureus-0017-00000082594-i01.jpg

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