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抗菌光动力疗法治疗急性淋巴细胞白血病患者的牙槽骨炎:一例报告

Antimicrobial Photodynamic Therapy for the Treatment of Alveolar Osteitis in a Patient With Acute Lymphoid Leukemia: A Case Report.

作者信息

Camilo-Silva Gabriela, Melo Sara Maria A, Moreira Francine C L, Campos Cerise C, Roriz Virgílio M

机构信息

Undergraduate Student, Faculty of Dentistry, Federal University of Goiás, Goiânia, Brazil.

Periodontics Specialist, Private Service, Anápolis, Goiás, Brazil.

出版信息

J Lasers Med Sci. 2021 Dec 12;12:e79. doi: 10.34172/jlms.2021.79. eCollection 2021.

Abstract

Acute lymphoid leukemia (ALL) is a malignant disease, the prognosis of which depends on the age of the patient and the treatment. The aim of this article was to report the treatment of this rare and interesting case of alveolar osteitis with antimicrobial photodynamic therapy (aPDT) in a patient with ALL that was resolved efficiently and quickly. A 33-year-old male diagnosed with ALL attended the public service, complaining of pain in the region of tooth 48, without function. Extraction was performed, and the patient returned for postoperative follow-up, complaining of severe pain in the area of the alveolus. Clinical examination revealed osteitis. The alveolus was treated using aPDT with 0.005% methylene blue photosensitizer, followed by the application of a low-level red laser at a wavelength of 660 nm (321 J/cm - site). After 15 days, soft tissue closure was observed and complete filling of the alveolus was observed radiographically with a 7-month follow-up. The authors suggest that aPDT can be an effective treatment of alveolar osteitis in a patient with ALL.

摘要

急性淋巴细胞白血病(ALL)是一种恶性疾病,其预后取决于患者年龄和治疗方法。本文旨在报告采用抗菌光动力疗法(aPDT)治疗一名ALL患者罕见且有趣的牙槽骨炎病例,该病例得到了有效且快速的解决。一名33岁被诊断为ALL的男性患者前来公共服务机构就诊,主诉48号牙区域疼痛,该牙已无功能。进行了拔牙手术,患者术后复诊时主诉牙槽区域剧痛。临床检查发现牙槽骨炎。使用0.005%亚甲蓝光敏剂通过aPDT治疗牙槽,随后应用波长为660 nm(321 J/cm² - 部位)的低强度红色激光。15天后,观察到软组织闭合,在7个月的随访中,影像学检查显示牙槽完全充填。作者认为,aPDT可以有效治疗ALL患者的牙槽骨炎。

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