评估土耳其爱琴海地区唇腭裂患者的颈椎异常。

Evaluation of the cervical vertebral anomalies in patients with cleft lip and palate in Aegean region of Turkey.

机构信息

Ali Cetinkaya Bulvari, Alsancak, Izmir, Turkey.

Department of Orthodontics, Ege University, Bornova, Izmir, Turkey.

出版信息

J Pak Med Assoc. 2021 Jan;71(1(B)):215-218. doi: 10.47391/JPMA.213.

DOI:10.47391/JPMA.213

PMID:35157652

Abstract

OBJECTIVE

To identify the cervical vertebral anomalies in patients with cleft lip and palate, and to compare unilateral and bilateral cleft lip and palate.

METHODS

The retrospective cohort study was conducted in 2018 at Department of Orthodontics, Ege University, Izmir, Turkey, and comprised non-deteriorated lateral cephalometric radiographs of non-syndromic patients which showed the entire cervical spine. The radiographs were divided into two groups, with group A having those of patients with cleft lip and palate exposure, and control group B having those with non-exposure. Within group A, unilateral and bilateral cleft lip and palate cases were compared. Data was analysed using SPSS 22.

RESULTS

Of the 220 subjects, 110(50%) were in group A with a mean age of 15±6.3 years, and 110(50%) were in group B with a mean age of 15±2.1 years. Within group A, 56(50.9%) subjects had unilateral and 54(49.1%) had bilateral cleft lip and palate. Cervical vertebral anomalies were found in 71(64.5%) patients and 45(40.9%) controls (p<0.001). Among those with bilateral condition, it was found in 41(75.9%) and in unilateral 56(56.6%) (p<0.05). Occipitalisation was 21(38.9%) in bilateral and 4(7.1%) in unilateral cases (p<0.001). Fusion was higher in bilateral patients 16(63%) compared to 23(41.1%) unilateral (p<0.05). Posterior arch deficiencies were found in 30(27.3%) patients in group A and 18(16.4%) controls in group B (p<0.05). Fusion was seen in 57(51.8%) group A patients and 33(30%) group B controls (p<0.001).

CONCLUSIONS

Cervical vertebral anomalies were mostly found in patients with cleft lip and palate. In patients with bilateral condition, more than one anomaly was seen.

摘要

目的

确定唇腭裂患者颈椎异常情况，并比较单侧和双侧唇腭裂。

方法

这是一项 2018 年在土耳其伊兹密尔 Ege 大学正畸系进行的回顾性队列研究，纳入显示整个颈椎的非综合征患者非恶化性侧位头颅侧位片。将这些头颅侧位片分为两组，A 组为唇腭裂暴露患者，B 组为无暴露患者。在 A 组内，比较单侧和双侧唇腭裂病例。使用 SPSS 22 进行数据分析。

结果

220 名受试者中，110 名（50%）在 A 组，平均年龄为 15±6.3 岁，110 名（50%）在 B 组，平均年龄为 15±2.1 岁。在 A 组内，56 名（50.9%）受试者为单侧唇腭裂，54 名（49.1%）为双侧唇腭裂。71 名（64.5%）患者和 45 名（40.9%）对照组存在颈椎异常（p<0.001）。双侧患者中，41 名（75.9%）存在枕骨化，单侧患者中 56 名（56.6%）存在枕骨化（p<0.05）。双侧患者融合发生率为 16（63%），单侧患者为 23（41.1%）（p<0.05）。A 组中有 30 名（27.3%）患者存在后弓缺陷，B 组中有 18 名（16.4%）对照组存在后弓缺陷（p<0.05）。A 组中有 57 名（51.8%）患者和 B 组中有 33 名（30%）对照组存在融合（p<0.001）。