Department of Developmental Medicine, Research Institute, Osaka Women's and Children's Hospital, Osaka, Japan; Department of Microbiology and Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Department of Clinical Laboratory, Fukuoka University Hospital, Fukuoka, Japan.
Diagn Microbiol Infect Dis. 2022 Apr;102(4):115633. doi: 10.1016/j.diagmicrobio.2022.115633. Epub 2022 Jan 15.
We observed an emerging resistance to β-lactams in a P. ananatis bacteremia case. Whole genome sequence analysis detected two β-lactamase genes as well as related genes that regulate the β-lactamase genes in the chromosome. The induction experiment resulted in the expression of the class A β-lactamase gene in the isolate.
我们在一例洋葱伯克霍尔德氏菌菌血症中观察到对β-内酰胺类抗生素的耐药性逐渐出现。全基因组序列分析在染色体中检测到两个β-内酰胺酶基因以及调节β-内酰胺酶基因的相关基因。诱导实验导致分离株中表达了 A 类β-内酰胺酶基因。
