Fleischer A, Schulman H, Farmakides G, Bracero L, Grunfeld L, Rochelson B, Koenigsberg M
Am J Obstet Gynecol. 1986 Apr;154(4):806-13. doi: 10.1016/0002-9378(86)90462-x.
Uterine and umbilical artery velocimetry was carried out on 71 women with hypertensive disorders in pregnancy. Three categories of hypertensive disease were diagnosed: chronic hypertension, preeclampsia, and chronic hypertension with superimposed preeclampsia. Clinical classifications describe the severity of disease effectively, primarily because the classification is based on the appearance of abnormal physical or laboratory findings. Doppler velocimetry of the uterine arteries shows that normal pregnancy occurs when the systolic/diastolic ratio is less than or equal to 2.6. When the ratio exceeds this level and there is a notch in the waveform, the pregnancy is complicated by stillbirth, premature birth, intrauterine growth retardation, and maternal preeclampsia. The positive and negative predictive value of the examination is 93% and 91%, respectively. It appears that this new technology will be an essential ingredient of optimum pregnancy surveillance.
对71例妊娠期高血压疾病患者进行了子宫和脐动脉血流速度测定。诊断出三类高血压疾病:慢性高血压、先兆子痫、慢性高血压合并先兆子痫。临床分类有效地描述了疾病的严重程度,主要是因为该分类基于异常体格检查或实验室检查结果。子宫动脉多普勒血流速度测定显示,收缩压/舒张压比值小于或等于2.6时为正常妊娠。当该比值超过此水平且波形出现切迹时,妊娠会并发死产、早产、胎儿宫内生长受限和母体先兆子痫。该检查的阳性和阴性预测值分别为93%和91%。看来这项新技术将成为最佳孕期监测的重要组成部分。