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肾移植受者的肺部充血严重程度不受动静脉内瘘功能的影响。

Lung Congestion Severity in Kidney Transplant Recipients Is Not Affected by Arteriovenous Fistula Function.

作者信息

Letachowicz Krzysztof, Królicka Anna, Tukiendorf Andrzej, Banasik Mirosław, Kamińska Dorota, Gołębiowski Tomasz, Kuriata-Kordek Magdalena, Madziarska Katarzyna, Mazanowska Oktawia, Krajewska Magdalena

机构信息

Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wrocław, Poland.

Faculty of Medicine, Wroclaw Medical University, 50-367 Wrocław, Poland.

出版信息

J Clin Med. 2022 Feb 5;11(3):842. doi: 10.3390/jcm11030842.

Abstract

Lung ultrasound is a bedside technique for the assessment of pulmonary congestion. The study aims to assess the severity of lung congestion in kidney transplant recipients (KTR) in relation to arteriovenous fistula (AVF) patency. One hundred fifty-seven patients at least 12 months after kidney transplantation were recruited to participate in a cross-sectional study. Apart from routine visits, lung ultrasound at 28 typical points was performed. The patients were assigned to either AVF+ or AVF- groups. The mean number of lung ultrasound B-lines (USBLs) was 5.14 ± 4.96 with no differences between groups: 5.5 ± 5.0 in AVF+ and 4.8 ± 4.9 in AVF-, = 0.35. The number and proportion of patients with no congestion (0-5 USBLs), mild congestion (6-15 USBLs), and moderate congestion (16-30 USBLs) were as follows: 101 (64.7%), 49 (31.4%), and 6 (3.8%), respectively. In multivariate analysis, only symptoms (OR 5.90; CI 2.43,14.3; = 0.0001), body mass index (BMI) (OR 1.09; CI 1.03,1.17; = 0.0046), and serum cholesterol level (OR 0.994; CI 0.998,1.000; = 0.0452) contributed significantly to the severity of lung congestion. Lung ultrasound is a valuable tool for the evaluation of KTR. Functioning AVF in KTR is not the major factor affecting the severity of pulmonary congestion.

摘要

肺部超声是一种用于评估肺充血情况的床旁检查技术。本研究旨在评估肾移植受者(KTR)中肺充血的严重程度与动静脉内瘘(AVF)通畅情况之间的关系。招募了157例肾移植术后至少12个月的患者参与一项横断面研究。除常规就诊外,在28个典型部位进行了肺部超声检查。患者被分为AVF+组或AVF-组。肺部超声B线(USBLs)的平均数量为5.14±4.96,两组之间无差异:AVF+组为5.5±5.0,AVF-组为4.8±4.9,P = 0.35。无充血(0 - 5条USBLs)、轻度充血(6 - 15条USBLs)和中度充血(16 - 30条USBLs)的患者数量及比例分别如下:101例(64.7%)、49例(31.4%)和6例(3.8%)。在多变量分析中,只有症状(OR 5.90;CI 2.43,14.3;P = 0.0001)、体重指数(BMI)(OR 1.09;CI 1.03,1.17;P = 0.0046)和血清胆固醇水平(OR 0.994;CI 0.998,1.000;P = 0.0452)对肺充血的严重程度有显著影响。肺部超声是评估KTR的一项有价值的工具。KTR中功能正常的AVF不是影响肺充血严重程度的主要因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8442/8836698/983f0d23174d/jcm-11-00842-g001.jpg

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