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重度贝尔面瘫的药物治疗与手术治疗比较

Comparison of Medical and Surgical Treatment in Severe Bell's Palsy.

作者信息

Kim Yong, Yeo Seung Geun, Rim Hwa Sung, Lee Jongha, Kim Dokyoung, Kim Sung Soo, Park Dong Choon, Byun Jae Yong, Kim Sang Hoon

机构信息

Department of Rehabilitation Medicine, College of Medicine, Kyung Hee University, Seoul 02447, Korea.

Department of Otorhinolaryngology, Head and Neck Surgery, College of Medicine, Kyung Hee University, Seoul 02447, Korea.

出版信息

J Clin Med. 2022 Feb 8;11(3):888. doi: 10.3390/jcm11030888.

DOI:10.3390/jcm11030888
PMID:35160337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8836601/
Abstract

(1) Background: The effectiveness of decompression surgery for Bell's palsy is controversial. This study investigated the effects of facial nerve decompression in patients with severe Bell's palsy who were expected to have a poor prognosis. (2) Methods: We retrospectively reviewed 1721 patients with Bell's palsy who visited the Kyung Hee University Hospital between January 2005 and December 2021. Of these, 45 patients with severe Bell's palsy were divided into two groups; 30 patients were treated conservatively with steroids and antiviral agents alone, while 15 patients underwent additional decompressive surgery after the conservative treatment. Outcomes were measured using House-Brackmann (H-B) grade for least 6 months after treatment was finished and conducted until full recovery was achieved. (3) Results: There was no significant difference in the rate of favorable recovery (H-B grade 1 or 2) between the surgery group and the conservative treatment group (75% vs. 70.0%, > 0.05). Although H-B grade improvement occurred in both groups, the degree of improvement was not significantly different between groups. (4) Conclusions: Facial nerve decompression surgery in severe Bell's palsy patients did not significantly improve prognosis beyond that offered by conservative treatment alone. Additional surgical decompression may not be necessary in patients with severe Bell's palsy if they receive sufficient conservative treatment.

摘要

(1) 背景:减压手术治疗贝尔面瘫的疗效存在争议。本研究调查了面神经减压术对预后较差的重度贝尔面瘫患者的影响。(2) 方法:我们回顾性分析了2005年1月至2021年12月期间就诊于庆熙大学医院的1721例贝尔面瘫患者。其中,45例重度贝尔面瘫患者分为两组;30例患者仅接受类固醇和抗病毒药物的保守治疗,而15例患者在保守治疗后接受了额外的减压手术。治疗结束后至少6个月使用House-Brackmann(H-B)分级来衡量预后,并持续观察直至完全恢复。(3) 结果:手术组和保守治疗组的良好恢复率(H-B 1级或2级)无显著差异(75%对70.0%,P>0.05)。虽然两组的H-B分级均有改善,但两组之间的改善程度无显著差异。(4) 结论:重度贝尔面瘫患者的面神经减压手术并不能显著改善预后,单纯保守治疗即可。如果重度贝尔面瘫患者接受了充分的保守治疗,则可能无需额外的手术减压。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/8836601/f4b9fe4cade7/jcm-11-00888-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/8836601/731347293962/jcm-11-00888-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/8836601/f4b9fe4cade7/jcm-11-00888-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/8836601/731347293962/jcm-11-00888-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/8836601/f4b9fe4cade7/jcm-11-00888-g002.jpg

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本文引用的文献

1
Association Between High Neutrophil to Lymphocyte Ratio and Delayed Recovery From Bell's Palsy.高中性粒细胞与淋巴细胞比值与贝尔麻痹延迟恢复之间的关联
Clin Exp Otorhinolaryngol. 2019 Aug;12(3):261-266. doi: 10.21053/ceo.2018.01018. Epub 2018 Dec 15.
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Systematic Review of Facial Nerve Outcomes After Middle Fossa Decompression and Transmastoid Decompression for Bell's Palsy With Complete Facial Paralysis.完全面瘫的贝尔氏面瘫患者接受中颅窝减压和经乳突减压后面神经结局的系统评价。
Otol Neurotol. 2018 Dec;39(10):1311-1318. doi: 10.1097/MAO.0000000000001979.
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Surgical Management of Acute Facial Palsy.
Toll 样受体在面神经损伤后面神经再生中的表达及作用。
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急性面神经麻痹的外科治疗
Otolaryngol Clin North Am. 2018 Dec;51(6):1077-1092. doi: 10.1016/j.otc.2018.07.005. Epub 2018 Aug 28.
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Facial nerve decompression.面神经减压术。
Curr Opin Otolaryngol Head Neck Surg. 2018 Oct;26(5):280-285. doi: 10.1097/MOO.0000000000000478.
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Delayed facial nerve decompression for severe refractory cases of Bell's palsy: a 25-year experience.延迟面神经减压治疗严重难治性贝尔麻痹:25 年经验。
J Otolaryngol Head Neck Surg. 2018 Jan 4;47(1):1. doi: 10.1186/s40463-017-0250-y.
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What is the normal value of the neutrophil-to-lymphocyte ratio?中性粒细胞与淋巴细胞比值的正常值是多少?
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Delayed surgical management is not effective for severe Bell's palsy after two months of onset.对于发病两个月后的重度贝尔面瘫,延迟手术治疗无效。
Int J Neurosci. 2016 Nov;126(11):989-95. doi: 10.3109/00207454.2015.1092144. Epub 2015 Oct 30.
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Delayed facial nerve decompression for Bell's palsy.贝尔面瘫的延迟面神经减压术。
Eur Arch Otorhinolaryngol. 2016 Jul;273(7):1755-60. doi: 10.1007/s00405-015-3762-y. Epub 2015 Aug 30.
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Facial nerve outcomes after middle fossa decompression for Bell's palsy.贝尔面瘫行中颅窝减压术后的面神经预后
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