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特定眼科护理液对水凝胶和硅水凝胶隐形眼镜润湿性及水合作用的影响——体外研究

Influence of Selected Ophthalmic Fluids on the Wettability and Hydration of Hydrogel and Silicone Hydrogel Contact Lenses-In Vitro Study.

作者信息

Chwalik-Pilszyk Gabriela, Wiśniewska Anna

机构信息

Department of Applied Mechanics and Biomechanics, Faculty of Mechanical Engineering, Tadeusz Kosciuszko Cracow University of Technology, 37 Jana Pawla II Av., 31-864 Cracow, Poland.

出版信息

Materials (Basel). 2022 Jan 25;15(3):930. doi: 10.3390/ma15030930.

DOI:10.3390/ma15030930
PMID:35160876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8839750/
Abstract

This study attempts to evaluate the effect of incubation in selected ophthalmic fluids on contact lenses (Etafilcon A, Omafilcon A, Narafilcon A, Senofilcon A). Four research groups differing in the incubation environment were created: (1) initial state, (2) contact lens solution (CLS), (3) contact lens solution and eye drops (ED) and (4) eye drops. Dehydration by gravimetric method and the contact angle (CA) by the sessile drop method were tested. The surface free energy (SFE) was also calculated with the use of several methods: Owens-Wendt, Wu, Neumann, and Neumann-Kwok. The greatest changes in the dehydration profile were observed for contact lenses incubated in ED. The most noticeable changes in CA values were observed for contact lenses incubated in ED, in which it was not possible to settle water drop after incubation. On the basis of SFE analysis, higher values were found for hydrogel contact lenses, e.g., according to the Owens-Wendt method, they ranged from 54.45 ± 6.56 mJ/m2 to 58.09 ± 4.86 mJ/m2, while in the case of silicone-hydrogel contact lenses, they ranged from 32.86 ± 3.47 mJ/m2 to 35.33 ± 6.56 mJ/m2. Incubation in all tested environments decreased the SFE values, but the differences were in most cases statistically insignificant. Calculating the SFE may be a useful method as it can be used to estimate the possibility of bacteria adhering to contact lens surfaces.

摘要

本研究旨在评估在选定的眼科液体中孵育对隐形眼镜(依他菲康A、奥马菲康A、那拉菲康A、森菲康A)的影响。创建了四个孵育环境不同的研究组:(1)初始状态,(2)隐形眼镜护理液(CLS),(3)隐形眼镜护理液和眼药水(ED),以及(4)眼药水。通过重量法测试脱水情况,通过静滴法测试接触角(CA)。还使用几种方法计算了表面自由能(SFE):欧文斯-温德特法、吴法、诺伊曼法和诺伊曼-郭法。在ED中孵育的隐形眼镜脱水情况变化最大。在ED中孵育的隐形眼镜CA值变化最明显,孵育后无法形成水滴。基于SFE分析,水凝胶隐形眼镜的值更高,例如,根据欧文斯-温德特法,其范围为54. .45±6.56 mJ/m²至58.09±4.86 mJ/m²,而硅水凝胶隐形眼镜的范围为32.86±3.47 mJ/m²至35.33±6.56 mJ/m²。在所有测试环境中孵育均降低了SFE值,但在大多数情况下差异无统计学意义。计算SFE可能是一种有用的方法,因为它可用于估计细菌附着在隐形眼镜表面的可能性。

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