Maldonado-Codina Carole, Morgan Philip B
Eurolens Research, Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom.
J Biomed Mater Res A. 2007 Nov;83(2):496-502. doi: 10.1002/jbm.a.31260.
This study investigated the water contact angles of five commercially available silicone hydrogel contact lenses (Acuvue Advance, Acuvue Oasys, Focus Night & Day, O2 Optix, and PureVision) using sessile drop and captive bubble techniques. The only lens type that showed a significant difference in water contact angle when measured by sessile drop direct from the blister compared with after 48 h of soaking/washing in saline was the Acuvue Advance lens (from 66 degrees to 96 degrees, respectively) (p=0.0002), presumably because of surface active agents within the blister solution. The water contact angle data split the lenses into two distinct groups (p<or=0.002). The Acuvue Advance, Acuvue Oasys, and PureVision lenses demonstrated relatively high sessile drop measures and relatively low captive bubble values (thereby displaying significant hysteresis) whereas the Focus Night & Day and O2 Optix lenses showed relatively low sessile drop measures and relatively high captive bubble values (with little hysteresis). Contact angle analysis of hydrogel lens surfaces is highly methodologically dependent and may be able to predict the clinical performance of contact lenses in vivo.
本研究采用静滴法和俘获气泡法，对五种市售硅水凝胶隐形眼镜（娇生全视线、爱尔康欧舒适、博士伦清朗日夜型、视康水润氧和视康睛智）的水接触角进行了研究。通过静滴法直接从泡罩中测量时，与在盐水中浸泡/清洗48小时后相比，唯一在水接触角上显示出显著差异的镜片类型是娇生全视线镜片（分别从66度变为96度）（p = 0.0002），这可能是由于泡罩溶液中的表面活性剂所致。水接触角数据将这些镜片分为两个不同的组（p≤0.002）。娇生全视线、爱尔康欧舒适和视康睛智镜片表现出相对较高的静滴测量值和相对较低的俘获气泡值（从而显示出显著的滞后现象），而博士伦清朗日夜型和视康水润氧镜片则显示出相对较低的静滴测量值和相对较高的俘获气泡值（滞后现象较小）。水凝胶镜片表面的接触角分析在很大程度上依赖于方法，并且可能能够预测隐形眼镜在体内的临床性能。
