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在健康和疾病中，质膜钙泵的结构、功能和调节。

Structure, Function and Regulation of the Plasma Membrane Calcium Pump in Health and Disease.

机构信息

Department of NMR-Based Structural Biology, Max Planck Institute (MPI) for Biophysical Chemistry, 37077 Gottingen, Germany.

出版信息

Int J Mol Sci. 2022 Jan 18;23(3):1027. doi: 10.3390/ijms23031027.

DOI:10.3390/ijms23031027
PMID:35162948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8835232/
Abstract

In this review, I summarize the present knowledge of the structural and functional properties of the mammalian plasma membrane calcium pump (PMCA). It is outlined how the cellular expression of the different spliced isoforms of the four genes are regulated under normal and pathological conditions.

摘要

在这篇综述中，我总结了哺乳动物质膜钙泵（PMCA）的结构和功能特性的现有知识。概述了在正常和病理条件下，四个基因的不同拼接异构体的细胞表达是如何受到调节的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/3c01b238922c/ijms-23-01027-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/cbbe731864ab/ijms-23-01027-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/ce426ba28824/ijms-23-01027-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/36c73513755f/ijms-23-01027-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/528706233a33/ijms-23-01027-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/3c01b238922c/ijms-23-01027-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/cbbe731864ab/ijms-23-01027-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/ce426ba28824/ijms-23-01027-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/36c73513755f/ijms-23-01027-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/528706233a33/ijms-23-01027-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/8835232/3c01b238922c/ijms-23-01027-g005.jpg

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