质膜钙泵（PMCA）：细胞质 Ca2+ 的调节、遗传多样性及其在亚质膜微区中的作用。
The Plasma Membrane Calcium Pump (PMCA): Regulation of Cytosolic Ca, Genetic Diversities and Its Role in Sub-plasma Membrane Microdomains.
机构信息
Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
出版信息
Adv Exp Med Biol. 2017;981:3-21. doi: 10.1007/978-3-319-55858-5_1.
PMID:29594855
Abstract
In this chapter the four different genes of the mammalian plasma membrane calcium ATPase (PMCA) and their spliced isoforms are discussed with respect to the structural and functional properties of PMCA, the tissue distribution of the different isoforms, including their differences during development. The importance of PMCA for regulating Ca signaling in microdomains under different conditions is also discussed.
摘要
在这一章中，将讨论哺乳动物质膜钙 ATP 酶 (PMCA) 的四个不同基因及其拼接异构体，内容涉及 PMCA 的结构和功能特性、不同异构体的组织分布，包括它们在发育过程中的差异。还讨论了 PMCA 在不同条件下调节微域 Ca 信号的重要性。
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