Huang T T, Blackwell S J, Lewis S R
Plast Reconstr Surg. 1978 Jul;62(1):32-6. doi: 10.1097/00006534-197807000-00004.
Over the past 25 years, 83 patients have been treated at our hospitals for poisonous snakebites of the hand. Prior to 1970, polyvalent antivenin was used, either alone or in conjunction with cryotherapy, steroids, or incision and suction methods. Hand deformities, due to tissue necrosis, were encountered in 15 of 22 patients (68%) treated by these methods. In contrast, excisional therapy, without the use of polyvalent antivenin, was the sole method of treatment in 61 patients seen since 1970. The incidence of hand deformity in them was 8.2%. We have concluded that early excision of the envenomated tissues will not only curtail systemic toxicity from the injected venom, but will also minimize the extent of local tissue damage.
在过去25年里，我院共收治了83例手部毒蛇咬伤患者。1970年以前，使用多价抗蛇毒血清，单独使用或与冷冻疗法、类固醇或切开吸引法联合使用。采用这些方法治疗的22例患者中有15例（68%）出现了因组织坏死导致的手部畸形。相比之下，自1970年以来，61例患者仅采用了切除疗法，未使用多价抗蛇毒血清。他们手部畸形的发生率为8.2%。我们得出的结论是，早期切除中毒组织不仅会减少注入毒液的全身毒性，还会将局部组织损伤的程度降至最低。
