• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

食管失弛缓症:复发症状的评估和治疗。

Esophageal Achalasia: Evaluation and Treatment of Recurrent Symptoms.

机构信息

Department of Surgery, University of Virginia, Charlottesville, VA, USA.

Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.

出版信息

World J Surg. 2022 Jul;46(7):1561-1566. doi: 10.1007/s00268-022-06466-4. Epub 2022 Feb 15.

DOI:10.1007/s00268-022-06466-4
PMID:35166877
Abstract

BACKGROUND

Esophageal achalasia is a primary esophageal motility disorder of unknown origin. Treatment is palliative and its goal is to decrease the resistance posed by a non-relaxing and often hypertensive lower esophageal sphincter. This goal can be accomplished by different treatment modalities such as pneumatic dilatation, laparoscopic myotomy or peroral endoscopic myotomy. In some patients, however, symptoms tend to recur overtime.

METHODS

A comprehensive literature search was performed on PubMed focused on the management of recurrent achalasia.

RESULTS

The available treatment modalities can be used, alone or in combination. The goal of treatment is to resolve/improve symptoms, avoiding an esophagectomy, an operation linked to significant morbidity.

CONCLUSIONS

The treatment of these patients is often very challenging, and the best results are obtained in centers where a multidisciplinary team-radiologists, gastroenterologists, and surgeons-is present.

摘要

背景

食管失弛缓症是一种病因不明的原发性食管动力障碍。治疗是姑息性的,其目的是降低非弛缓性且常伴有高血压的食管下括约肌的阻力。这一目标可以通过不同的治疗方式来实现,例如气动扩张、腹腔镜肌切开术或经口内镜肌切开术。然而,在一些患者中,症状往往会随着时间的推移而复发。

方法

在 PubMed 上进行了一项针对复发性失弛缓症治疗的全面文献检索。

结果

可单独或联合使用各种治疗方法。治疗的目的是缓解/改善症状,避免行食管切除术,因为这种手术与较高的发病率相关。

结论

这些患者的治疗通常极具挑战性,在多学科团队(放射科医生、胃肠病学家和外科医生)存在的中心可以获得最佳结果。

相似文献

1
Esophageal Achalasia: Evaluation and Treatment of Recurrent Symptoms.食管失弛缓症:复发症状的评估和治疗。
World J Surg. 2022 Jul;46(7):1561-1566. doi: 10.1007/s00268-022-06466-4. Epub 2022 Feb 15.
2
Esophageal achalasia: current diagnosis and treatment.食管失弛缓症:当前的诊断与治疗。
Expert Rev Gastroenterol Hepatol. 2018 Jul;12(7):711-721. doi: 10.1080/17474124.2018.1481748. Epub 2018 Jun 8.
3
Minimally invasive myotomy for the treatment of esophageal achalasia: evolution of the surgical procedure and the therapeutic algorithm.微创肌切开术治疗食管贲门失弛缓症:手术方法的演变及治疗算法
Surg Laparosc Endosc Percutan Tech. 2012 Apr;22(2):83-7. doi: 10.1097/SLE.0b013e318243368f.
4
Surgical Options for End-Stage Achalasia.贲门失弛缓症终末期的手术选择。
Curr Gastroenterol Rep. 2023 Nov;25(11):267-274. doi: 10.1007/s11894-023-00889-2. Epub 2023 Aug 30.
5
Laparoscopic Heller Myotomy with Dor Fundoplication: An Operation that has Withstood the Test of Time.腹腔镜 Heller 肌切开术加 Dor 胃底折叠术:经得起时间考验的手术。
World J Surg. 2022 Jul;46(7):1531-1534. doi: 10.1007/s00268-022-06580-3. Epub 2022 May 6.
6
Peroral endoscopic myotomy for esophageal motility disorders.经口内镜下肌切开术治疗食管动力障碍。
Esophagus. 2020 Jan;17(1):11-18. doi: 10.1007/s10388-019-00693-w. Epub 2019 Oct 12.
7
Achalasia: Diagnosis, Management and Surveillance.贲门失弛缓症:诊断、治疗和监测。
Gastroenterol Clin North Am. 2021 Dec;50(4):721-736. doi: 10.1016/j.gtc.2021.07.001. Epub 2021 Oct 2.
8
Systematic Review and Bayesian Network Meta-Analysis Comparing Laparoscopic Heller Myotomy, Pneumatic Dilatation, and Peroral Endoscopic Myotomy for Esophageal Achalasia.比较腹腔镜贲门肌切开术、气囊扩张术和经口内镜下肌切开术治疗贲门失弛缓症的系统评价和贝叶斯网络荟萃分析
J Laparoendosc Adv Surg Tech A. 2020 Feb;30(2):147-155. doi: 10.1089/lap.2019.0432. Epub 2019 Jul 31.
9
Multidisciplinary Approach to Esophageal Achalasia: A Single Center Experience.食管贲门失弛缓症的多学科治疗方法:单中心经验
J Laparoendosc Adv Surg Tech A. 2017 Apr;27(4):358-362. doi: 10.1089/lap.2016.0594. Epub 2017 Jan 18.
10
Achalasia: what to do in the face of failures of Heller myotomy.贲门失弛缓症:Heller 肌切开术失败时该怎么办。
Ann N Y Acad Sci. 2020 Dec;1481(1):236-246. doi: 10.1111/nyas.14440. Epub 2020 Jul 26.

引用本文的文献

1
Revisional surgery for persistent dysphagia plus Roux Y gastric bypass robot-assisted in a patient with obesity. About a case.肥胖患者持续性吞咽困难的翻修手术加机器人辅助 Roux Y 胃旁路手术。关于一个病例。
J Surg Case Rep. 2024 Mar 17;2024(3):rjae149. doi: 10.1093/jscr/rjae149. eCollection 2024 Mar.
2
Evaluating the Non-conventional Achalasia Treatment Modalities.评估贲门失弛缓症的非常规治疗方式。
Front Med (Lausanne). 2022 Jun 24;9:941464. doi: 10.3389/fmed.2022.941464. eCollection 2022.

本文引用的文献

1
Laparoscopic Revisional Surgery After Failed Heller Myotomy for Esophageal Achalasia: Long-Term Outcome at a Single Tertiary Center.腹腔镜修正手术治疗食管失弛缓症 Heller 肌切开术失败:单中心长期疗效。
J Gastrointest Surg. 2021 Sep;25(9):2208-2217. doi: 10.1007/s11605-021-05041-x. Epub 2021 Jun 7.
2
Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia.特发性贲门失弛缓症患者的内镜或手术肌切开术。
N Engl J Med. 2019 Dec 5;381(23):2219-2229. doi: 10.1056/NEJMoa1905380.
3
Effect of Peroral Endoscopic Myotomy vs Pneumatic Dilation on Symptom Severity and Treatment Outcomes Among Treatment-Naive Patients With Achalasia: A Randomized Clinical Trial.
经口内镜肌切开术与气囊扩张治疗原发性贲门失弛缓症患者的疗效比较:一项随机临床试验。
JAMA. 2019 Jul 9;322(2):134-144. doi: 10.1001/jama.2019.8859.
4
A Thousand and One Laparoscopic Heller Myotomies for Esophageal Achalasia: a 25-Year Experience at a Single Tertiary Center.一千零一次腹腔镜 Heller 肌切开术治疗食管失弛缓症:单中心 25 年经验。
J Gastrointest Surg. 2019 Jan;23(1):23-35. doi: 10.1007/s11605-018-3956-x. Epub 2018 Sep 20.
5
Laparoscopic Heller Myotomy Versus Peroral Endoscopic Myotomy (POEM) for Achalasia: A Systematic Review and Meta-analysis.腹腔镜 Heller 肌切开术与经口内镜肌切开术(POEM)治疗贲门失弛缓症:系统评价和荟萃分析。
Ann Surg. 2018 Mar;267(3):451-460. doi: 10.1097/SLA.0000000000002311.
6
Efficacy and Safety of Peroral Endoscopic Myotomy for Treatment of Achalasia After Failed Heller Myotomy.经口内镜肌切开术治疗 Heller 肌切开术失败后贲门失弛缓症的疗效和安全性。
Clin Gastroenterol Hepatol. 2017 Oct;15(10):1531-1537.e3. doi: 10.1016/j.cgh.2017.01.031. Epub 2017 Feb 9.
7
The course of achalasia one to four decades after initial treatment.贲门失弛缓症初始治疗后1至4十年的病程。
Aliment Pharmacol Ther. 2017 Feb;45(4):553-560. doi: 10.1111/apt.13888. Epub 2016 Dec 7.
8
Long-term outcome of peroral endoscopic myotomy for esophageal achalasia in patients with previous Heller myotomy.曾接受过贲门肌层切开术的食管失弛缓症患者经口内镜下肌切开术的长期疗效
Surg Endosc. 2017 Jun;31(6):2596-2601. doi: 10.1007/s00464-016-5267-1. Epub 2016 Oct 3.
9
Efficacy of pneumodilation in achalasia after failed Heller myotomy.贲门失弛缓症患者行Heller肌切开术失败后气囊扩张术的疗效
Neurogastroenterol Motil. 2016 Nov;28(11):1741-1746. doi: 10.1111/nmo.12875. Epub 2016 Jul 11.
10
Peroral Endoscopic Myotomy for Esophageal Achalasia: Outcomes of the First 100 Patients With Short-term Follow-up.经口内镜下肌切开术治疗食管贲门失弛缓症:首批100例患者短期随访结果
Ann Surg. 2016 Jan;263(1):82-7. doi: 10.1097/SLA.0000000000000992.