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食管失弛缓症:复发症状的评估和治疗。

Esophageal Achalasia: Evaluation and Treatment of Recurrent Symptoms.

机构信息

Department of Surgery, University of Virginia, Charlottesville, VA, USA.

Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.

出版信息

World J Surg. 2022 Jul;46(7):1561-1566. doi: 10.1007/s00268-022-06466-4. Epub 2022 Feb 15.

Abstract

BACKGROUND

Esophageal achalasia is a primary esophageal motility disorder of unknown origin. Treatment is palliative and its goal is to decrease the resistance posed by a non-relaxing and often hypertensive lower esophageal sphincter. This goal can be accomplished by different treatment modalities such as pneumatic dilatation, laparoscopic myotomy or peroral endoscopic myotomy. In some patients, however, symptoms tend to recur overtime.

METHODS

A comprehensive literature search was performed on PubMed focused on the management of recurrent achalasia.

RESULTS

The available treatment modalities can be used, alone or in combination. The goal of treatment is to resolve/improve symptoms, avoiding an esophagectomy, an operation linked to significant morbidity.

CONCLUSIONS

The treatment of these patients is often very challenging, and the best results are obtained in centers where a multidisciplinary team-radiologists, gastroenterologists, and surgeons-is present.

摘要

背景

食管失弛缓症是一种病因不明的原发性食管动力障碍。治疗是姑息性的,其目的是降低非弛缓性且常伴有高血压的食管下括约肌的阻力。这一目标可以通过不同的治疗方式来实现,例如气动扩张、腹腔镜肌切开术或经口内镜肌切开术。然而,在一些患者中,症状往往会随着时间的推移而复发。

方法

在 PubMed 上进行了一项针对复发性失弛缓症治疗的全面文献检索。

结果

可单独或联合使用各种治疗方法。治疗的目的是缓解/改善症状,避免行食管切除术,因为这种手术与较高的发病率相关。

结论

这些患者的治疗通常极具挑战性,在多学科团队(放射科医生、胃肠病学家和外科医生)存在的中心可以获得最佳结果。

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