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Bone marrow metastasis from advanced gastric cancer complicated with disseminated intravascular coagulation: a highly aggressive but manageable disease subtype.

作者信息

Zhai Xiaohui, Wang Caiqin, Li Shanshan, Cao Taiyuan, Du Ge, Zhang Yan, Chen Dianke, Fan Xinjuan, Huang Yan, Hu Ping, Zheng Jian, Yang Zuli, Lian Lei, Peng Junsheng, Lan Ping, Xiao Jian

机构信息

Department of Medical Oncology, The Sixth Affiliated Hospital of Sun-Yat Sen University, Guangzhou, Guangdong, 510655, P. R. China.

Guangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, P. R. China.

出版信息

Cancer Commun (Lond). 2022 Apr;42(4):350-354. doi: 10.1002/cac2.12277. Epub 2022 Feb 15.

DOI:10.1002/cac2.12277
PMID:35167192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9017754/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a8a/9017754/41ee80c744d7/CAC2-42-350-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a8a/9017754/41ee80c744d7/CAC2-42-350-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a8a/9017754/41ee80c744d7/CAC2-42-350-g001.jpg

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FDP/FIB ratio serves as a novel biomarker for diagnosing bone marrow invasion in gastric cancer and predicting patient prognosis\.纤维蛋白降解产物/纤维蛋白原（FDP/FIB）比值是诊断胃癌骨髓浸润及预测患者预后的一种新型生物标志物。
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本文引用的文献

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Cancer incidence, mortality, and burden in China: a time-trend analysis and comparison with the United States and United Kingdom based on the global epidemiological data released in 2020.中国癌症发病率、死亡率和疾病负担的变化趋势分析：基于 2020 年全球公布的流行病学数据与美国和英国的比较
Cancer Commun (Lond). 2021 Oct;41(10):1037-1048. doi: 10.1002/cac2.12197. Epub 2021 Jul 20.
2
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020：全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
3
Long-term survival of a patient with gastric cancer with bone marrow metastasis receiving S-1 plus oxaliplatin beyond three years: a case report and literature review.
一名胃癌伴骨髓转移患者接受S-1联合奥沙利铂治疗后长期生存超过三年：病例报告及文献综述
Front Oncol. 2024 Aug 6;14:1449212. doi: 10.3389/fonc.2024.1449212. eCollection 2024.
4
Mechanism and clinical progression of solid tumors bone marrow metastasis.实体瘤骨髓转移的机制与临床进展
Front Pharmacol. 2024 May 6;15:1390361. doi: 10.3389/fphar.2024.1390361. eCollection 2024.
5
Single-cell RNA sequencing reveals immune cell dysfunction in the peripheral blood of patients with highly aggressive gastric cancer.单细胞 RNA 测序揭示了侵袭性强的胃癌患者外周血免疫细胞功能障碍。
Cell Prolif. 2024 May;57(5):e13591. doi: 10.1111/cpr.13591. Epub 2024 Feb 6.
6
Induction of filopodia formation by α-Actinin-2 via RelA with a feedforward activation loop promoting overt bone marrow metastasis of gastric cancer.α-辅肌动蛋白-2 通过 RelA 形成的伪足诱导作用，具有促进胃癌明显骨髓转移的前馈激活环。
J Transl Med. 2023 Jun 19;21(1):399. doi: 10.1186/s12967-023-04156-w.
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Front Oncol. 2023 Feb 22;13:1019702. doi: 10.3389/fonc.2023.1019702. eCollection 2023.
Tissue macrophages: heterogeneity and functions.
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BMC Biol. 2017 Jun 29;15(1):53. doi: 10.1186/s12915-017-0392-4.
4
Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2).1995 - 2009年全球癌症生存情况监测：对来自67个国家279个基于人群的登记处的25,676,887例患者的个体数据进行分析（CONCORD - 2）
Lancet. 2015 Mar 14;385(9972):977-1010. doi: 10.1016/S0140-6736(14)62038-9. Epub 2014 Nov 26.
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Prominent hypereosinophilia with disseminated intravascular coagulation as an unusual presentation of advanced gastric cancer.显著嗜酸性粒细胞增多症合并弥散性血管内凝血作为晚期胃癌的一种不寻常表现。
Intern Med. 2014;53(6):563-9. doi: 10.2169/internalmedicine.53.1483.
6
Natural history of malignant bone disease in gastric cancer: final results of a multicenter bone metastasis survey.胃癌恶性骨病的自然史：多中心骨转移调查的最终结果。
PLoS One. 2013 Oct 28;8(10):e74402. doi: 10.1371/journal.pone.0074402. eCollection 2013.
7
Clinicopathologic features and clinical outcomes of gastric cancer that initially presents with disseminated intravascular coagulation: a retrospective study.以弥散性血管内凝血为首发表现的胃癌的临床病理特征和临床转归：一项回顾性研究。
J Gastroenterol Hepatol. 2010 Sep;25(9):1537-42. doi: 10.1111/j.1440-1746.2010.06289.x.
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Sequential chemotherapy with methotrexate and 5-fluorouracil for chemotherapy-naive advanced gastric cancer with disseminated intravascular coagulation at initial diagnosis.初诊时伴有弥漫性血管内凝血的化疗初治晚期胃癌采用甲氨蝶呤和 5-氟尿嘧啶序贯化疗。
J Cancer Res Clin Oncol. 2010 Feb;136(2):243-8. doi: 10.1007/s00432-009-0655-8.
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Disseminated intravascular coagulation at presentation of advanced gastric cancer.晚期胃癌初诊时的弥散性血管内凝血
Isr Med Assoc J. 2006 Dec;8(12):853-5.
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Sequential methotrexate and 5-fluorouracil therapy for gastric cancer patients with bone metastasis.序贯甲氨蝶呤和5-氟尿嘧啶治疗胃癌骨转移患者
Gastric Cancer. 2000 Aug 4;3(1):19-23. doi: 10.1007/pl00011684.