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压力与免疫之间的相互作用引发COVID-19患者的带状疱疹感染:综述

Interplay between stress and immunity triggers herpes zoster infection in COVID-19 patients: a review.

作者信息

Rahangdale Rakesh Ravishankar, Tender Tenzin, Balireddy Sridevi, Pasupuleti Mukesh, Hariharapura Raghu Chandrashekar

机构信息

Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal- 576104, India.

Microbiology Division, Council of Scientific and Industrial Research, Central Drug Research Institute, Lucknow- 226031, India.

出版信息

Can J Microbiol. 2022 May;68(5):303-314. doi: 10.1139/cjm-2021-0242. Epub 2022 Feb 15.

Abstract

Coronavirus disease 2019 (COVID-19) is a potential health threat in the highly mobile society of the world. There are also concerns regarding the occurrence of co-infections occurring in COVID-19 patients. Herpes zoster (HZ) is currently being reported as a co-infection in COVID-19 patients. It is a varicella-zoster virus induced viral infection affecting older and immunocompromised individuals. Reactivation of HZ infection in COVID-19 patients are emerging and the mechanism of reactivation is still unknown. The most convincing argument is that increased psychological and immunological stress leads to HZ in COVID-19 patients; this review justifies this argument.

摘要

2019年冠状病毒病(COVID-19)在当今世界高度流动的社会中构成了潜在的健康威胁。人们还担心COVID-19患者会出现合并感染。目前有报道称,带状疱疹(HZ)是COVID-19患者的一种合并感染。它是由水痘-带状疱疹病毒引起的病毒感染,影响老年人和免疫功能低下的个体。COVID-19患者中HZ感染的再激活情况正在出现,而再激活的机制仍不清楚。最有说服力的观点是,心理和免疫压力增加导致了COVID-19患者发生HZ;本综述对这一观点进行了论证。

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