接种过疫苗的墨西哥成年人 COVID-19 肺炎的独立危险因素。
Independent risk factors of COVID-19 pneumonia in vaccinated Mexican adults.
机构信息
Departamento de Epidemiología, Unidad de Medicina Familiar No. 19, Instituto Mexicano del Seguro Social, Av. Javier Mina 301, Col. Centro, C.P. 28000, Colima, Colima, México; Facultad de Medicina, Universidad de Colima, Av. Universidad 333, Col. Las Víboras, C.P. 28040, Colima, Colima, México.
Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
出版信息
Int J Infect Dis. 2022 May;118:244-246. doi: 10.1016/j.ijid.2022.02.003. Epub 2022 Feb 12.
OBJECTIVES
To evaluate host factors associated with the risk of coronavirus disease 2019 (COVID-19) pneumonia in vaccinated adults.
METHODS
A cohort study was conducted in Mexico, and data from 1607 adults with confirmed illness, with a positive history of COVID-19 vaccination, were analyzed. Risk ratios (RR) and 95% confidence intervals (CI) were computed as a measure of the significance of the associations between putative risk factors and the prevalence of COVID-19 pneumonia in vaccinated subjects.
RESULTS
The overall risk of pneumonia was 1.98 per 1000 person-days. In the multiple regression analysis, older subjects, those with a history of smoking (current), obesity, and type 2 diabetes mellitus were at increased risk of pneumonia.
CONCLUSIONS
Our results suggest that the effectiveness of COVID-19 vaccines may be reduced in a subset of adults who are older aged, smokers, obese, or have type 2 diabetes mellitus.
目的
评估与接种成年人 2019 年冠状病毒病（COVID-19）肺炎风险相关的宿主因素。
方法
在墨西哥进行了一项队列研究，对 1607 名有确诊疾病且有 COVID-19 疫苗接种阳性史的成年人的数据进行了分析。风险比（RR）和 95%置信区间（CI）被计算为衡量潜在危险因素与接种疫苗者 COVID-19 肺炎患病率之间关联的显著性的指标。
结果
肺炎的总体风险为每 1000 人日 1.98 例。在多元回归分析中，年龄较大、有吸烟史（当前）、肥胖和 2 型糖尿病的患者患肺炎的风险增加。
结论
我们的结果表明，COVID-19 疫苗的有效性可能会降低一部分年龄较大、吸烟、肥胖或患有 2 型糖尿病的成年人。
Zotero 插件